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Fmoc-D-Phe-OH

CAS 86123-10-6C24H21NO4Chemical Synthesis

Fmoc-D-Phe-OH (CAS: 86123-10-6), with the molecular formula C24H21NO4 and a molecular weight of 387.43 g/mol, is a protected amino acid derivative. It is primarily utilised in solid-phase peptide synthesis (SPPS) and as a building block in chemical biology and organic synthesis. This compound serves as a crucial intermediate for creating complex peptides and peptidomimetics, aiding in research and development within pharmaceutical and biochemical fields.

IUPAC
Fmoc-D-phenylalanine
Synonyms
Fmoc-D-phenylalanine
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Fmoc-D-Phe-OH (C24H21NO4) — chemical structure, CAS 86123-10-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine
01 /Applications

Peptide Synthesis

Fmoc-D-Phe-OH is widely used in the Fmoc/tBu strategy for solid-phase peptide synthesis. The N-terminal Fmoc group allows for orthogonal deprotection strategies, facilitating the sequential addition of amino acids to a growing peptide chain.

Chemical Biology Research

As a non-natural amino acid derivative, it is employed in chemical biology to introduce specific structural or functional modifications into peptides. This enables the study of peptide-protein interactions and the development of novel biomolecules.

Organic Synthesis Intermediate

Beyond peptides, this compound serves as a valuable chiral building block in complex organic synthesis. Its defined stereochemistry and functional groups can be leveraged for the creation of diverse molecular architectures.

02 /Properties
Molecular weight387.43
Empirical formulaC24H21NO4
Assay≥98.0%
Storage temperature2-8°C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
86123-10-6
MDL number
MFCD00062955
Beilstein registry
4767931
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-D-Phe-OH used for?

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Fmoc-D-Phe-OH (CAS: 86123-10-6) is used as a protected amino acid derivative, primarily for solid-phase peptide synthesis (SPPS), in chemical biology research, and as a chiral building block in organic synthesis.

What are the CAS number and molecular formula for Fmoc-D-Phe-OH?

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The CAS number for Fmoc-D-Phe-OH is 86123-10-6, and its molecular formula is C24H21NO4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Fmoc-D-Phe-OH with a purity of ≥98.0%. This product is typically supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should Fmoc-D-Phe-OH be handled and stored?

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Handle Fmoc-D-Phe-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the chemical at refrigeration temperatures between 2-8°C.

Is Fmoc-D-Phe-OH a controlled substance?

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The provided data does not indicate that Fmoc-D-Phe-OH (CAS: 86123-10-6) is a controlled substance.

How is Fmoc-D-Phe-OH packed, shipped, and exported?

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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing for shipping and export of Fmoc-D-Phe-OH in compliance with international regulations.

How can I request a sample or a quote for Fmoc-D-Phe-OH?

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To request a sample or a quote for Fmoc-D-Phe-OH, please contact the Tech Serve Solutions sales team through the official website or designated contact channels.

Need Fmoc-D-Phe-OH in a specific grade or volume?