Fmoc-D-Phe-OH
Fmoc-D-Phe-OH (CAS: 86123-10-6), with the molecular formula C24H21NO4 and a molecular weight of 387.43 g/mol, is a protected amino acid derivative. It is primarily utilised in solid-phase peptide synthesis (SPPS) and as a building block in chemical biology and organic synthesis. This compound serves as a crucial intermediate for creating complex peptides and peptidomimetics, aiding in research and development within pharmaceutical and biochemical fields.
- IUPAC
- Fmoc-D-phenylalanine
- Synonyms
- Fmoc-D-phenylalanine

Peptide Synthesis
Fmoc-D-Phe-OH is widely used in the Fmoc/tBu strategy for solid-phase peptide synthesis. The N-terminal Fmoc group allows for orthogonal deprotection strategies, facilitating the sequential addition of amino acids to a growing peptide chain.
Chemical Biology Research
As a non-natural amino acid derivative, it is employed in chemical biology to introduce specific structural or functional modifications into peptides. This enables the study of peptide-protein interactions and the development of novel biomolecules.
Organic Synthesis Intermediate
Beyond peptides, this compound serves as a valuable chiral building block in complex organic synthesis. Its defined stereochemistry and functional groups can be leveraged for the creation of diverse molecular architectures.
| Molecular weight | 387.43 |
|---|---|
| Empirical formula | C24H21NO4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phe-OH used for?
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Fmoc-D-Phe-OH (CAS: 86123-10-6) is used as a protected amino acid derivative, primarily for solid-phase peptide synthesis (SPPS), in chemical biology research, and as a chiral building block in organic synthesis.
What are the CAS number and molecular formula for Fmoc-D-Phe-OH?
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The CAS number for Fmoc-D-Phe-OH is 86123-10-6, and its molecular formula is C24H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Phe-OH with a purity of ≥98.0%. This product is typically supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-D-Phe-OH be handled and stored?
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Handle Fmoc-D-Phe-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the chemical at refrigeration temperatures between 2-8°C.
Is Fmoc-D-Phe-OH a controlled substance?
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The provided data does not indicate that Fmoc-D-Phe-OH (CAS: 86123-10-6) is a controlled substance.
How is Fmoc-D-Phe-OH packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing for shipping and export of Fmoc-D-Phe-OH in compliance with international regulations.
How can I request a sample or a quote for Fmoc-D-Phe-OH?
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To request a sample or a quote for Fmoc-D-Phe-OH, please contact the Tech Serve Solutions sales team through the official website or designated contact channels.
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