Fmoc-D-Phg-OH
Fmoc-D-Phg-OH (CAS: 111524-95-9), with the molecular formula C23H19NO4 and a molecular weight of 373.40 g/mol, is a chiral derivative of phenylglycine. It is a valuable building block in organic synthesis, particularly within peptide chemistry and the development of unnatural amino acid derivatives. Its protected form facilitates controlled peptide chain elongation. This compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- Fmoc-D-α-phenylglycine
- Synonyms
- Fmoc-D-alpha-phenylglycine

Peptide Synthesis
Fmoc-D-Phg-OH serves as a crucial Fmoc-protected unnatural amino acid for incorporation into peptides. Its D-configuration and phenyl side chain allow for the modification of peptide structure and properties, influencing biological activity and stability.
Chemical Synthesis
This compound is employed as a chiral building block in complex organic synthesis. It enables the introduction of a non-proteinogenic amino acid moiety into target molecules, aiding in the creation of novel chemical entities.
Chemical Biology Research
Utilised in the exploration of structure-activity relationships, Fmoc-D-Phg-OH can be incorporated into research probes or peptidomimetics to study biological interactions and pathways.
Unnatural Amino Acid Derivatives
It is a key precursor for synthesising a range of unnatural amino acid derivatives with potential applications in drug discovery and materials science.
| Molecular weight | 373.40 |
|---|---|
| Empirical formula | C23H19NO4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phg-OH used for?
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Fmoc-D-Phg-OH is used as a protected unnatural amino acid building block in peptide synthesis, as a chiral intermediate in organic synthesis, and in chemical biology research to create novel molecular structures.
What are the CAS number and formula for Fmoc-D-Phg-OH?
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The CAS number is 111524-95-9 and the empirical formula (Hill notation) is C23H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Phg-OH with an assay of ≥98.0%. This compound is supplied for research and development; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling considerations for Fmoc-D-Phg-OH?
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Fmoc-D-Phg-OH is classified with hazard statement H413. It requires the use of eyeshields, gloves, and an appropriate respirator filter (type N95 or P1). Store at 2-8°C. Users should consult the Safety Data Sheet (SDS) for full handling information.
How is Fmoc-D-Phg-OH packed, shipped, and exported?
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Fmoc-D-Phg-OH is carefully packaged to maintain its integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Fmoc-D-Phg-OH?
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To request a sample or a quote, please contact our sales team through the website or by telephone, providing the product name and CAS number.
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