2,3,4-Trimethoxybenzyl alcohol
2,3,4-Trimethoxybenzyl alcohol (CAS 71989-96-3) is an organic compound with the molecular formula (CH3O)3C6H2CH2OH and a molecular weight of 198.22 g/mol. This aromatic alcohol, characterised by three methoxy substituents and a hydroxymethyl group on the benzene ring, serves as a valuable building block in organic synthesis. It is particularly utilised for introducing a trimethoxybenzyl moiety into various molecular structures, facilitating further chemical transformations in research and development.
- Synonyms
- 71989-96-3, (CH3O)3C6H2CH2OH
Protecting Group Chemistry
2,3,4-Trimethoxybenzyl alcohol can be employed as a reagent to introduce the 2,3,4-trimethoxybenzyl protecting group. This group is useful in multi-step organic syntheses, particularly in the modification of nucleosides, where it can be selectively attached to hydroxyl functionalities.
Organic Synthesis Intermediate
As a functionalised aromatic alcohol, this compound acts as an intermediate in the synthesis of more complex organic molecules. Its structure allows for various chemical modifications, making it a versatile building block for researchers in medicinal chemistry and materials science.
Nucleoside Modification
Historically, 2,3,4-Trimethoxybenzyl alcohol has been specifically cited for its use in introducing a benzyl group onto the 2′-hydroxyl position of purine ribonucleosides, aiding in the study and synthesis of modified nucleic acid analogues.
| Molecular weight | 198.22 |
|---|---|
| Linear formula | (CH3O)3C6H2CH2OH |
| Assay | 97% |
| Boiling point | 105 °C/25 mmHg(lit.) |
| Density | 1.151 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.532(lit.) |
| Application | 2,3,4-Trimethoxybenzyl alcohol was used to introduce a benzyl group onto the 2′-OH of purine ribonucleoside1. |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4-Trimethoxybenzyl alcohol used for?
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2,3,4-Trimethoxybenzyl alcohol is used as a building block in organic synthesis and for introducing benzyl groups onto molecules, such as in the modification of purine ribonucleosides.
What is the CAS number and formula for 2,3,4-Trimethoxybenzyl alcohol?
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The CAS number is 71989-96-3 and the linear formula is (CH3O)3C6H2CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,4-Trimethoxybenzyl alcohol with a minimum assay of 97%. This product is typically considered for research or technical applications and is not supplied as USP, BP, or EP grade.
What are the safety precautions for handling 2,3,4-Trimethoxybenzyl alcohol?
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Handle with care. Essential personal protective equipment includes eyeshields and gloves. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive hazard information and handling procedures.
How is 2,3,4-Trimethoxybenzyl alcohol packaged and shipped?
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Products are carefully packaged to ensure safe transport and are exported globally by Tech Serve Solutions in compliance with international shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample of 2,3,4-Trimethoxybenzyl alcohol, please contact the Tech Serve Solutions sales team through our website or by calling us directly.
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