2,3,4-Trimethoxyphenylboronic acid
2,3,4-Trimethoxyphenylboronic acid (CAS: 118062-05-8) is an organoboron compound with the molecular formula (CH3O)3C6H2B(OH)2 and a molecular weight of 212.01 g/mol. This trisubstituted aryl boronic acid serves as a key reactant, primarily in Suzuki-Miyaura cross-coupling reactions. Its specific substitution pattern makes it a valuable building block in organic synthesis for creating complex molecules, particularly within pharmaceutical research and materials science.
- IUPAC
- 2,3,4-Trimethoxybenzeneboronic acid
- Synonyms
- 118062-05-8(CH3O)3C6H2B(OH)22,3,4-Trimethoxybenzeneboronic acid
Suzuki-Miyaura Cross-Coupling Reactions
2,3,4-Trimethoxyphenylboronic acid is an effective coupling partner in palladium-catalyzed Suzuki-Miyaura reactions. This application is crucial for the formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex organic structures.
Organic Synthesis Intermediate
As a functionalized boronic acid, it acts as a versatile intermediate in multi-step organic synthesis. It allows for the introduction of the 2,3,4-trimethoxyphenyl moiety into diverse molecular frameworks.
Pharmaceutical Research
The compound is employed in the development of novel pharmaceutical agents. Its structural features can be incorporated into drug candidates to explore structure-activity relationships and optimize pharmacological properties.
Materials Science
In materials science, 2,3,4-Trimethoxyphenylboronic acid can be utilized in the synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) or specialized polymers, where its electronic or structural properties are beneficial.
| Molecular weight | 212.01 |
|---|---|
| Linear formula | (CH3O)3C6H2B(OH)2 |
| Storage temperature | 2-8°C |
| Application | Reactant for:• Suzuki-Miyaura cross-coupling reactions1,2,3,4,5 |
| Melting point | 74-79 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4-Trimethoxyphenylboronic acid primarily used for?
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2,3,4-Trimethoxyphenylboronic acid is primarily used as a reactant in Suzuki-Miyaura cross-coupling reactions for organic synthesis, particularly in pharmaceutical research and materials science.
What are the CAS number and chemical formula for 2,3,4-Trimethoxyphenylboronic acid?
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The CAS number for 2,3,4-Trimethoxyphenylboronic acid is 118062-05-8, and its linear formula is (CH3O)3C6H2B(OH)2.
What grade and purity does Tech Serve Solutions supply for 2,3,4-Trimethoxyphenylboronic acid?
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Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,3,4-Trimethoxyphenylboronic acid be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store the material at 2-8°C to maintain stability.
Is 2,3,4-Trimethoxyphenylboronic acid a controlled substance?
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Based on the provided data, there is no indication that 2,3,4-Trimethoxyphenylboronic acid is a controlled substance.
How can I request a sample or quote for 2,3,4-Trimethoxyphenylboronic acid?
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To request a sample or quote, please contact the Tech Serve Solutions sales department via our website or by phone, providing the product name and CAS number (118062-05-8).
How is 2,3,4-Trimethoxyphenylboronic acid packed and exported?
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Tech Serve Solutions packs and exports chemicals adhering to international shipping regulations for hazardous materials. Specific packaging details will be provided upon order confirmation.
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