Fmoc-D-Phe(4-F)-OH
Fmoc-D-Phe(4-F)-OH (CAS: 177966-64-2) is a fluorinated, unnatural amino acid derivative with the molecular formula C24H20FNO4. This compound serves as a crucial building block in peptide synthesis and medicinal chemistry research. Its incorporation allows for the introduction of specific physicochemical properties into peptide sequences, aiding in the development of novel therapeutic agents and biochemical probes.
- IUPAC
- Fmoc-4-fluoro-D-phenylalanine
- Synonyms
- Fmoc-4-fluoro-D-phenylalanine
Peptide Synthesis
Utilised as a protected amino acid in solid-phase or solution-phase peptide synthesis. The Fmoc protecting group facilitates stepwise elongation of peptide chains.
Medicinal Chemistry
Incorporated into novel molecular structures for drug discovery and development. The fluorine atom can modulate metabolic stability, binding affinity, and lipophilicity.
Biochemical Research
Employed in the creation of modified peptides for studying protein-protein interactions, enzyme mechanisms, or as components of labelled probes.
Analytical Standards
Can be used as a reference standard in analytical chemistry, particularly in chromatographic methods for identifying or quantifying related compounds.
| Molecular weight | 405.42 |
|---|---|
| Empirical formula | C24H20FNO4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phe(4-F)-OH used for?
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Fmoc-D-Phe(4-F)-OH is primarily used as a protected building block in peptide synthesis and for applications in medicinal chemistry and biochemical research. It is particularly valuable for introducing fluorinated phenylalanine residues into peptides.
What are the CAS number and formula for Fmoc-D-Phe(4-F)-OH?
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The CAS number for Fmoc-D-Phe(4-F)-OH is 177966-64-2, and its molecular formula is C24H20FNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Phe(4-F)-OH with an assay of ≥98.0%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Fmoc-D-Phe(4-F)-OH?
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Handling Fmoc-D-Phe(4-F)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance carries a WGK Germany classification of 3, indicating it is hazardous to water.
How is Fmoc-D-Phe(4-F)-OH shipped and stored?
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Fmoc-D-Phe(4-F)-OH is shipped and exported by Tech Serve Solutions according to standard chemical shipping regulations. It should be stored at refrigeration temperatures between 2-8°C to maintain its integrity.
How can I request a sample or quote for Fmoc-D-Phe(4-F)-OH?
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To request a sample or obtain a quotation for Fmoc-D-Phe(4-F)-OH, please contact the Tech Serve Solutions sales department via our website or direct enquiry channels.
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