N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (CAS: 25952-53-8, C8H17N3 · HCl) is a versatile chemical reagent with a molecular weight of 191.70 g/mol. It is widely utilised in various chemical coupling and modification reactions. Its primary applications lie in areas such as protein modification, structural analysis, and in facilitating amine coupling reactions for self-assembly processes in scientific research and development.
- IUPAC
- N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride,EDAC,EDC hydrochloride,EDC,WSC hydrochloride
- Synonyms
- EDACEDC hydrochlorideEDCWSC hydrochlorideN-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride
Amine Coupling Reactions
This carbodiimide is instrumental in facilitating amine coupling reactions, notably used in the self-assembly of tethered bilayer lipid membranes in research settings.
Antibody Derivatization
It has been employed for the derivatization of antibodies, such as linking antibodies against COX5b to carboxylated polystyrene microspheres for diagnostic or research applications.
Protein Modification and Analysis
As a heterobifunctional cross-linking reagent, it plays a role in protein modification and structural analysis, contributing to proteomics research.
| Molecular weight | 191.70 |
|---|---|
| Empirical formula | C8H17N3 · HCl |
| Assay | ≥98.0% (AT) |
| Grade | purum |
| Solubility | H2O: soluble1 gm/10 ml, clear to very slightly hazy, colorless to very faintly yellow |
| Storage temperature | −20°C |
| Application | N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride has been used for amine coupling reaction during self-assembly of the tethered bilayer lipid membrane.1 It has also been used for derivatizing antibody against COX5b to carboxylated polystyrene microspheres.2 |
| Melting point | 110-115 °C(lit.)110-115 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride used for?
+
This compound is primarily used for amine coupling reactions, antibody derivatization, and in protein modification and structural analysis within research and development contexts.
What are the CAS number and formula for N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride?
+
The CAS number is 25952-53-8, and the empirical formula is C8H17N3 · HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product at a purity of ≥98.0% (AT), with a grade of 'purum'. We do not represent this product as USP, BP, or EP grade.
How should N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride be handled safely?
+
Due to its hazardous nature, handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. It is classified as causing skin irritation, serious eye damage, and respiratory irritation.
How is this chemical packed, shipped, and exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and adherence to international shipping regulations for safe transport.
How can I request a quote or sample?
+
To request a quote or sample, please visit the Tech Serve Solutions website or contact our sales department directly with your specific requirements.
▶ Related products
Acrylamide
Molecular Biology
Agarose
Molecular Biology
N,N′-Methylenebisacrylamide
Molecular Biology
Zinc sulfate solution
Molecular Biology
(±)-Jasmonic acid
C12H18O3
Molecular Biology
(−)-cis,trans-Abscisic acid
Molecular Biology
(2,4-Dichlorophenoxy)acetic acid sodium salt monohydrate
Molecular Biology
(2R,5R)-Bis(hydroxymethyl)-(3R,4R)-dihydroxypyrrolidine
Molecular Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis