PTH-4-hydroxyproline
4-Hydroxy-L-proline Phenylthiohydantoin (PTH-4-hydroxyproline), CAS 81703-65-3, with the molecular formula C12H12N2O2S and a molecular weight of 248.30 g/mol, is a vital reagent in biochemical research. It is predominantly utilized in protein sequencing and structural analysis, playing a crucial role in identifying amino acid residues within protein chains.

Protein Sequencing
PTH-4-hydroxyproline is used as a reagent in the Edman degradation process for automated protein sequencing. It aids in the identification of amino acid residues, particularly hydroxyproline, within polypeptide chains.
Protein Structural Analysis
This compound contributes to the detailed structural characterization of proteins. Its application in sequencing helps elucidate the primary structure, which is fundamental for understanding protein function and conformation.
Proteomics Research
Within the broader field of proteomics, PTH-4-hydroxyproline serves as a specialized tool for analyzing protein components. It supports high-throughput studies and the characterization of complex protein mixtures.
| Molecular weight | 248.30 |
|---|---|
| Empirical formula | C12H12N2O2S |
| Storage temperature | −20°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PTH-4-hydroxyproline primarily used for?
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PTH-4-hydroxyproline is primarily used as a reagent in protein sequencing and structural analysis, particularly in the identification of amino acid residues within protein chains.
What are the CAS number and molecular formula for PTH-4-hydroxyproline?
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The CAS number for PTH-4-hydroxyproline is 81703-65-3, and its molecular formula is C12H12N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research purposes. The specific purity and grade information is available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for PTH-4-hydroxyproline?
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According to the supplied data, this compound has a WGK Germany classification of 3, indicating it is hazardous to water. Always consult the Safety Data Sheet (SDS) for comprehensive handling, storage, and disposal guidelines.
How is PTH-4-hydroxyproline typically stored?
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PTH-4-hydroxyproline should be stored at -20°C to maintain its stability and efficacy.
How can I request a sample or quote for PTH-4-hydroxyproline?
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To request a sample or obtain a quotation, please contact our sales team via the website or direct email, specifying the product CAS number 81703-65-3.
Does Tech Serve Solutions export PTH-4-hydroxyproline?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including PTH-4-hydroxyproline.
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