Fmoc-Phe(4-NO2)-OH
Fmoc-Phe(4-NO2)-OH (CAS: 95753-55-2), with the molecular formula C24H20N2O6 and a molecular weight of 432.43, is a specialised unnatural amino acid derivative. It is primarily employed in peptide chemistry and chemical synthesis as a protected building block. This compound is valuable for introducing a nitro-substituted phenylalanine residue into peptide sequences, facilitating further chemical modifications and research in chemical biology.
- IUPAC
- Fmoc-4-nitro-L-phenylalanine
Peptide Synthesis
Fmoc-Phe(4-NO2)-OH serves as a crucial building block in solid-phase and solution-phase peptide synthesis. The Fmoc protecting group allows for controlled coupling in automated synthesizers, while the nitro group on the phenylalanine side chain can be used for subsequent modifications or as a reporter group.
Chemical Biology Research
This compound is utilised in chemical biology to create peptides with specific functionalities. The nitro group can be reduced to an amine, enabling conjugation to other molecules or the formation of novel structures for probing biological systems.
Organic Synthesis Intermediate
As a derivative of phenylalanine, Fmoc-Phe(4-NO2)-OH can be an intermediate in the synthesis of more complex organic molecules. Its defined structure and reactive groups make it suitable for various synthetic transformations beyond peptide chemistry.
| Molecular weight | 432.43 |
|---|---|
| Empirical formula | C24H20N2O6 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe(4-NO2)-OH used for?
+
Fmoc-Phe(4-NO2)-OH is primarily used in peptide synthesis and chemical biology research as a building block for introducing a nitro-substituted phenylalanine residue. It also serves as an intermediate in organic synthesis.
What are the CAS number and formula for Fmoc-Phe(4-NO2)-OH?
+
The CAS number for Fmoc-Phe(4-NO2)-OH is 95753-55-2, and its molecular formula is C24H20N2O6.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Fmoc-Phe(4-NO2)-OH with a purity of ≥96.0% (HPLC). This product is intended for research and development use and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Fmoc-Phe(4-NO2)-OH be handled and stored?
+
Handle Fmoc-Phe(4-NO2)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store the compound at 2-8°C.
Is Fmoc-Phe(4-NO2)-OH a controlled substance?
+
The provided data does not indicate that Fmoc-Phe(4-NO2)-OH is a controlled substance.
How is this chemical exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring reliable international shipment of products like Fmoc-Phe(4-NO2)-OH.
How can I request a quote or sample?
+
To request a quote or sample of Fmoc-Phe(4-NO2)-OH, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis