Fmoc-Phe(4-I)-OH
Fmoc-Phe(4-I)-OH (CAS 82565-68-2) is a protected amino acid derivative with the molecular formula C24H20INO4 and a molecular weight of 513.32. This compound serves as a crucial building block in peptide synthesis, particularly for introducing modified phenylalanine residues. It is also utilised in chemical biology and as an analytical standard, enabling researchers to develop and validate complex molecular structures and analytical methods in various scientific disciplines.
- IUPAC
- Fmoc-4-iodo-L-phenylalanine
Peptide Synthesis
Fmoc-Phe(4-I)-OH is extensively used as a protected amino acid in solid-phase peptide synthesis (SPPS). It allows for the controlled incorporation of 4-iodo-L-phenylalanine into peptide chains, facilitating the creation of complex peptide structures and peptidomimetics.
Chemical Biology
The unique structure of this compound makes it valuable in chemical biology research. It can be employed in the synthesis of labelled peptides or as a probe to study protein-protein interactions and enzymatic mechanisms.
Analytical Standards
As an analytical standard, Fmoc-Phe(4-I)-OH is used for the identification and quantification of related compounds in chromatography and other analytical techniques. Its well-defined structure aids in method development and validation.
Organic Synthesis
Beyond peptide chemistry, this iodo-phenylalanine derivative can be a versatile intermediate in broader organic synthesis. The iodine atom provides a handle for further functionalization via cross-coupling reactions.
| Molecular weight | 513.32 |
|---|---|
| Empirical formula | C24H20INO4 |
| Assay | ≥97.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe(4-I)-OH used for?
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Fmoc-Phe(4-I)-OH is primarily used in peptide synthesis as a protected amino acid building block for introducing 4-iodo-L-phenylalanine. It also finds applications in chemical biology and as an analytical standard.
What are the CAS number and molecular formula for Fmoc-Phe(4-I)-OH?
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The CAS number for Fmoc-Phe(4-I)-OH is 82565-68-2, and its molecular formula is C24H20INO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-Phe(4-I)-OH?
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Tech Serve Solutions supplies Fmoc-Phe(4-I)-OH with a purity of ≥97.0%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should Fmoc-Phe(4-I)-OH be handled and stored safely?
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Handle Fmoc-Phe(4-I)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Store the compound at 2-8°C to maintain its stability.
Is Fmoc-Phe(4-I)-OH a controlled substance?
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Based on the provided data, there is no indication that Fmoc-Phe(4-I)-OH is a controlled substance.
How is Fmoc-Phe(4-I)-OH packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed to ensure safe transport and are exported worldwide. Specific packaging details are available upon request.
How can I request a quote or sample for Fmoc-Phe(4-I)-OH?
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To request a quote or a sample of Fmoc-Phe(4-I)-OH, please contact our sales team through the website or by phone. Our experts will assist you with your inquiry.
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