Fmoc-Phg-OH
Fmoc-Phg-OH (CAS: 102410-65-1) is a chiral building block with the molecular formula C23H19NO4 and a molecular weight of 373.40 g/mol. This Fmoc-protected unnatural amino acid derivative is a valuable reagent in chemical synthesis and peptide chemistry. It is utilized in the development of novel peptides and peptidomimetics, often employed as an analytical standard in research and development settings. The compound is supplied with a typical purity of ≥98.0% by HPLC.
- IUPAC
- Fmoc-L-α-phenylglycine

Peptide Synthesis
Fmoc-Phg-OH serves as a key component in solid-phase and solution-phase peptide synthesis, particularly for incorporating unnatural amino acid residues. Its use allows for the creation of peptides with modified structures and enhanced properties.
Chemical Biology Research
This compound is employed in chemical biology to construct modified peptides for probing biological systems. It facilitates research into protein-protein interactions, enzyme mechanisms, and the development of novel therapeutic agents.
Analytical Standards
As an analytical standard, Fmoc-Phg-OH is used for method development and validation in chromatography, such as HPLC. It ensures accurate identification and quantification of related compounds in complex mixtures.
Drug Discovery and Development
The incorporation of Fmoc-Phg-OH into peptidomimetic scaffolds can lead to the discovery of new drug candidates. Its unique structure can confer improved stability, bioavailability, and target affinity.
| Molecular weight | 373.40 |
|---|---|
| Empirical formula | C23H19NO4 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D +81±3°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phg-OH primarily used for?
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Fmoc-Phg-OH is primarily used in peptide synthesis and chemical biology research for the incorporation of unnatural amino acid residues into peptides and peptidomimetics. It also serves as an analytical standard.
What are the CAS number and molecular formula for Fmoc-Phg-OH?
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The CAS number for Fmoc-Phg-OH is 102410-65-1, and its molecular formula is C23H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Phg-OH with a purity of ≥98.0% by HPLC. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-Phg-OH be handled and stored?
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Fmoc-Phg-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the chemical at 2-8°C.
Is Fmoc-Phg-OH a controlled substance?
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The provided data does not indicate that Fmoc-Phg-OH is a controlled substance.
How are Tech Serve Solutions' chemicals packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring secure and compliant packaging for international shipment.
How can I request a sample or a quote for Fmoc-Phg-OH?
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To request a sample or a quote for Fmoc-Phg-OH, please contact our sales team through the details provided on our website.
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