Fmoc-Pro-OH
Fmoc-Pro-OH (CAS 71989-31-6) is N-(9-Fluorenylmethoxycarbonyl)-L-proline, a crucial derivative of the amino acid proline. With the molecular formula C20H19NO4 and a molecular weight of 337.37 g/mol, it is widely employed in peptide synthesis. Its primary role is as a building block for incorporating proline residues into peptide chains, particularly in solid-phase peptide synthesis (SPPS).
- IUPAC
- N-(9-Fluorenylmethoxycarbonyl)-L-proline,Fmoc-L-proline
- Synonyms
- N-(9-Fluorenylmethoxycarbonyl)-L-prolineFmoc-L-proline
Peptide Synthesis
Fmoc-Pro-OH is a fundamental building block in the synthesis of peptides, especially for solid-phase peptide synthesis (SPPS). It allows for the controlled introduction of proline residues into peptide sequences.
Chemical Biology Research
Used in research to create modified peptides with specific structural or functional properties, enabling the study of biological processes at a molecular level.
Organic Synthesis
Serves as a chiral synthon in various organic synthesis pathways, leveraging the unique structure of proline for complex molecule construction.
| Molecular weight | 337.37 |
|---|---|
| Empirical formula | C20H19NO4 |
| Assay | ≥99.0% (HPLC) |
| Optical activity | [α]20/D −32±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 117-118 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Pro-OH used for?
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Fmoc-Pro-OH is primarily used as a protected amino acid derivative in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), for the incorporation of proline residues into peptide chains.
What is the CAS number and formula for Fmoc-Pro-OH?
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The CAS number for Fmoc-Pro-OH is 71989-31-6, and its empirical formula is C20H19NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-Pro-OH?
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Tech Serve Solutions supplies Fmoc-Pro-OH with an assay of ≥99.0% (HPLC). This product is intended for research and chemical synthesis and is not represented as USP, BP, or EP grade.
How should Fmoc-Pro-OH be handled and stored safely?
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Fmoc-Pro-OH should be handled with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. It should be stored at 2-8°C.
Is Fmoc-Pro-OH a controlled substance?
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Based on the provided data, Fmoc-Pro-OH (CAS 71989-31-6) is not indicated as a controlled substance.
How is Fmoc-Pro-OH shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and can arrange for the compliant packaging and export of Fmoc-Pro-OH to meet international shipping regulations.
How can I request a quote or sample for Fmoc-Pro-OH?
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To request a quote or a sample of Fmoc-Pro-OH, please contact the Tech Serve Solutions sales team via the website or direct contact details provided.
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