Fmoc-Phe-OPfp
Fmoc-Phe-OPfp (CAS: 86060-92-6; Formula: C30H20F5NO4; MW: 553.48) is a derivative of the amino acid phenylalanine, functionalised with a pentafluorophenyl ester. This activated ester form is primarily utilised in solid-phase peptide synthesis (SPPS) for efficient coupling. Its controlled reactivity allows for the sequential addition of phenylalanine residues in the construction of complex peptide chains for research and development.
- IUPAC
- N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine pentafluorophenyl ester,Fmoc-L-phenylalanine pentafluorophenyl ester
- Synonyms
- N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine pentafluorophenyl esterFmoc-L-phenylalanine pentafluorophenyl ester
Peptide Synthesis
Fmoc-Phe-OPfp serves as a crucial activated amino acid derivative in solid-phase peptide synthesis. The pentafluorophenyl ester facilitates efficient amide bond formation with free amino groups on a growing peptide chain.
Chemical Biology Research
This compound is employed in the synthesis of peptides and peptidomimetics for studies in chemical biology, enabling the exploration of protein function and biological pathways.
Organic Synthesis
As a protected amino acid derivative with an activated ester, Fmoc-Phe-OPfp can be used in various organic synthesis routes requiring the controlled introduction of phenylalanine moieties.
| Molecular weight | 553.48 |
|---|---|
| Empirical formula | C30H20F5NO4 |
| Assay | ≥96.0% |
| Storage temperature | 2-8°C |
| Melting point | 149-151 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe-OPfp used for?
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Fmoc-Phe-OPfp is primarily used as an activated amino acid derivative in solid-phase peptide synthesis (SPPS) for the efficient coupling of phenylalanine into peptide chains.
What is the CAS number and formula for Fmoc-Phe-OPfp?
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The CAS number for Fmoc-Phe-OPfp is 86060-92-6, and its empirical formula is C30H20F5NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Phe-OPfp with a purity of ≥96.0%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Phe-OPfp be handled and stored?
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Handle Fmoc-Phe-OPfp with appropriate personal protective equipment, including eyeshields and gloves. Store at 2-8°C. Refer to the safety data sheet for comprehensive handling guidelines.
Is Fmoc-Phe-OPfp a controlled substance?
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The provided data does not indicate that Fmoc-Phe-OPfp is a controlled substance.
How can I request a sample or quote for Fmoc-Phe-OPfp?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (86060-92-6).
How is Fmoc-Phe-OPfp packed and shipped?
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Fmoc-Phe-OPfp is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions following all relevant shipping regulations.
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