Fmoc-Phe(4-CN)-OH
Fmoc-Phe(4-CN)-OH (CAS: 173963-93-4) is a cyanophenylalanine derivative with the molecular formula C25H20N2O4 and a molecular weight of 412.44 g/mol. This unnatural amino acid derivative is a valuable building block in peptide chemistry and chemical synthesis. It is employed in the development of novel peptides and peptidomimetics, finding applications in chemical biology research and the synthesis of complex organic molecules requiring specific structural modifications.
- IUPAC
- Fmoc-4-cyano-L-phenylalanine
- Synonyms
- Fmoc-4-cyano-L-phenylalanine

Peptide Synthesis
Utilised as a modified amino acid in solid-phase or solution-phase peptide synthesis to introduce a nitrile functional group and a modified aromatic ring. This facilitates the creation of peptides with unique electronic or structural properties.
Chemical Biology
Serves as a probe or building block in chemical biology for studying protein-ligand interactions or developing new biochemical assays. The cyano group can be a reporter or a site for further functionalisation.
Organic Synthesis
Acts as a versatile intermediate in the synthesis of complex organic molecules and pharmaceutical lead compounds. The protected amino acid functionality and the nitrile group offer diverse synthetic routes.
| Molecular weight | 412.44 |
|---|---|
| Empirical formula | C25H20N2O4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe(4-CN)-OH used for?
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Fmoc-Phe(4-CN)-OH is used in peptide synthesis, chemical biology, and organic synthesis as a modified amino acid building block for creating novel peptides and complex molecules.
What is the CAS number and molecular formula for Fmoc-Phe(4-CN)-OH?
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The CAS number is 173963-93-4, and the molecular formula is C25H20N2O4.
What grade and purity does Tech Serve Solutions supply for Fmoc-Phe(4-CN)-OH?
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Tech Serve Solutions supplies Fmoc-Phe(4-CN)-OH with a purity of ≥98.0% (HPLC). This product is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for Fmoc-Phe(4-CN)-OH?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. The substance has a WGK Germany rating of 3.
How is Fmoc-Phe(4-CN)-OH packed, shipped, and exported?
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Fmoc-Phe(4-CN)-OH is packed and stored at 2-8°C. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all necessary regulations.
How can I request a sample or quote for Fmoc-Phe(4-CN)-OH?
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To request a sample or obtain a quote for Fmoc-Phe(4-CN)-OH, please contact our sales team through the website or by phone, providing your specific requirements.
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