Fmoc-Phe(3-Me)-OH
Fmoc-Phe(3-Me)-OH (CAS 211637-74-0), a modified phenylalanine derivative with the empirical formula C25H23NO4 and a molecular weight of 401.45 g/mol, is a key building block in advanced peptide synthesis. This unnatural amino acid derivative is utilised in chemical biology and synthesis for creating peptides with unique structural and functional properties, offering researchers a tool for developing novel biomolecules.
- IUPAC
- Fmoc-3-methyl-L-phenylalanine

Peptide Synthesis
Fmoc-Phe(3-Me)-OH is employed as a protected unnatural amino acid in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the introduction of specific structural modifications into peptide chains, influencing their folding, stability, and biological activity.
Chemical Biology Research
This compound serves as a valuable reagent in chemical biology for constructing peptides with tailored properties. It enables the study of structure-activity relationships and the development of peptide-based probes or therapeutics.
Drug Discovery and Development
As a building block for unnatural peptides, Fmoc-Phe(3-Me)-OH aids in the design and synthesis of novel peptide drug candidates. Its unique structure can impart enhanced pharmacological profiles, such as increased resistance to enzymatic degradation.
| Molecular weight | 401.45 |
|---|---|
| Empirical formula | C25H23NO4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe(3-Me)-OH used for?
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Fmoc-Phe(3-Me)-OH is used as a protected unnatural amino acid derivative in chemical synthesis, particularly for creating modified peptides in peptide chemistry and chemical biology research.
What is the CAS number and formula for Fmoc-Phe(3-Me)-OH?
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The CAS number for Fmoc-Phe(3-Me)-OH is 211637-74-0 and its empirical formula is C25H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Phe(3-Me)-OH with an assay of ≥98.0%. This product is suitable for research and technical applications. TSS does not represent this product as USP, BP, or EP grade.
How should Fmoc-Phe(3-Me)-OH be handled and stored?
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Handle Fmoc-Phe(3-Me)-OH with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Store the compound refrigerated at 2-8°C.
Is Fmoc-Phe(3-Me)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Phe(3-Me)-OH is a controlled substance.
How is Fmoc-Phe(3-Me)-OH shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, handling the packing and export of products like Fmoc-Phe(3-Me)-OH according to international regulations.
How can I request a quote or sample for Fmoc-Phe(3-Me)-OH?
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Please contact the Tech Serve Solutions sales team through our website or direct contact details to request a quotation or a sample of Fmoc-Phe(3-Me)-OH.
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