Fmoc-Phe(3-F)-OH
Fmoc-Phe(3-F)-OH (CAS: 198560-68-8), with the molecular formula C24H20FNO4 and a molecular weight of 405.42, is a valuable unnatural amino acid derivative. It serves as a specialised building block in peptide chemistry and chemical synthesis. Its unique fluorinated phenyl ring makes it suitable for applications in chemical biology and the development of novel peptide-based therapeutics and research tools.
- IUPAC
- Fmoc-3-fluoro-L-phenylalanine
Peptide Synthesis
Utilised as a key building block in the solid-phase or solution-phase synthesis of peptides. The incorporation of Fmoc-Phe(3-F)-OH allows for the introduction of a fluorinated phenylalanine residue, potentially influencing peptide conformation, stability, and binding interactions.
Chemical Biology Research
Serves as a tool for investigating protein structure-function relationships and for developing peptide-based probes. The fluorine atom can be useful for NMR studies or for modulating the physicochemical properties of biomolecules.
Drug Discovery and Development
Incorporated into peptide or peptidomimetic drug candidates to enhance metabolic stability, receptor binding affinity, or pharmacokinetic profiles. Its unnatural structure can lead to novel therapeutic agents.
Materials Science
May be employed in the development of novel biomaterials or functional polymers where specific recognition or structural properties are desired.
| Molecular weight | 405.42 |
|---|---|
| Empirical formula | C24H20FNO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe(3-F)-OH used for?
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Fmoc-Phe(3-F)-OH is primarily used as a specialised building block in peptide synthesis, chemical biology research, and drug discovery, particularly for introducing a fluorinated phenylalanine residue.
What is the CAS number and chemical formula for Fmoc-Phe(3-F)-OH?
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The CAS number is 198560-68-8 and the chemical formula is C24H20FNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Phe(3-F)-OH with a purity of ≥97.0% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Fmoc-Phe(3-F)-OH be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Store at 2-8°C. The WGK Germany classification is 3.
Is Fmoc-Phe(3-F)-OH a controlled substance?
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Based on the provided data, there is no indication that Fmoc-Phe(3-F)-OH is a controlled substance.
How are products like Fmoc-Phe(3-F)-OH packed, shipped, and exported?
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Products are carefully packed according to industry best practices and regulatory requirements for safe shipping and international export. Specific packaging details will be provided with your order confirmation.
How can I request a quote or sample of Fmoc-Phe(3-F)-OH?
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Please contact our sales team via the website or direct email to request a quotation or to inquire about obtaining a sample of Fmoc-Phe(3-F)-OH.
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