Fmoc-Phe(4-Boc2-guanidino)-OH

CAS 187283-25-6C35H40N4O8Chemical Synthesis

Fmoc-Phe(4-Boc2-guanidino)-OH (CAS: 187283-25-6), a derivative of phenylalanine with the empirical formula C35H40N4O8, offers a molecular weight of 644.71. This protected amino acid is a valuable building block in complex peptide synthesis and chemical biology research. Its specific functionalization supports the introduction of modified guanidino groups into peptides, facilitating studies of protein interactions and drug discovery.

IUPAC: Fmoc-4-(N,N′-di-Boc-guanidino)-L-phenylalanine

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Fmoc-Phe(4-Boc2-guanidino)-OH (C35H40N4O8) — chemical structure, CAS 187283-25-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine Derivatives

01 /Applications

Peptide Synthesis

Utilised as a protected unnatural amino acid derivative in solid-phase and solution-phase peptide synthesis. It allows for the incorporation of modified phenylalanine residues into peptide chains.

Chemical Biology

Serves as a tool for constructing peptides with specific functionalities for investigating biological pathways and molecular interactions. The protected guanidino group can be deprotected to reveal a modified arginine mimic.

Drug Discovery

Employed in the synthesis of novel peptide-based therapeutics and probes. Its unique structure aids in the development of peptidomimetics with enhanced stability or modified binding properties.

Organic Synthesis

A versatile intermediate in the synthesis of complex organic molecules where a protected guanidino-phenylalanine moiety is required.

02 /Properties

Molecular weight	644.71
Empirical formula	C35H40N4O8
Assay	≥90% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

187283-25-6

MDL number

MFCD02092975

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Phe(4-Boc2-guanidino)-OH used for?

Fmoc-Phe(4-Boc2-guanidino)-OH is primarily used as a protected unnatural amino acid in peptide synthesis and chemical biology for incorporating modified phenylalanine residues into peptides. It is also valuable in drug discovery and general organic synthesis.

What is the CAS number and molecular formula?

The CAS number is 187283-25-6 and the molecular formula is C35H40N4O8.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Phe(4-Boc2-guanidino)-OH with an assay of ≥90% by HPLC. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should Fmoc-Phe(4-Boc2-guanidino)-OH be handled?

Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. Storage at 2-8°C is advised.

Is this compound a controlled substance?

The provided data does not indicate that Fmoc-Phe(4-Boc2-guanidino)-OH is a controlled substance.

How is this product shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product can be shipped and exported worldwide, adhering to all relevant regulations.

How can I request a sample or quote?

To request a sample or obtain a quote for Fmoc-Phe(4-Boc2-guanidino)-OH, please contact the Tech Serve Solutions sales department through the website or by phone.