Fmoc-Phe(4-Br)-OH

CAS 198561-04-5C24H20BrNO4Chemical Synthesis

Fmoc-Phe(4-Br)-OH (CAS: 198561-04-5) is a valuable building block for peptide synthesis, featuring a brominated phenylalanine residue protected with the Fmoc group. This unnatural amino acid derivative is crucial in chemical biology and synthesis for creating peptides with modified properties. Its structure allows for the incorporation of a bromine atom, enabling further chemical modifications or acting as a probe. It is supplied by TSS with an assay of ≥98.0% for research and development purposes.

IUPAC: Fmoc-4-bromo-L-phenylalanine

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Fmoc-Phe(4-Br)-OH (C24H20BrNO4) — chemical structure, CAS 198561-04-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine DerivativesSilicon-BasedSynthetic Reagents

01 /Applications

Peptide Synthesis

Fmoc-Phe(4-Br)-OH serves as a key intermediate in solid-phase and solution-phase peptide synthesis. Its Fmoc protecting group facilitates controlled chain elongation in peptide assembly.

Chemical Biology Research

This compound is used to introduce a brominated phenylalanine residue into peptides, creating probes for studying protein structure, function, and interactions.

Drug Discovery and Development

Incorporating unnatural amino acids like Fmoc-Phe(4-Br)-OH into peptide sequences can lead to the development of novel therapeutic agents with enhanced stability and biological activity.

Organic Synthesis

The bromine atom on the phenyl ring offers a site for further functionalization through various cross-coupling reactions, expanding its utility in complex organic synthesis.

02 /Properties

Molecular weight	466.32
Empirical formula	C24H20BrNO4
Assay	≥98.0%

03 /Safety & handling

Hazard statements

H413May cause long-lasting harmful effects to aquatic life

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

198561-04-5

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Phe(4-Br)-OH used for?

Fmoc-Phe(4-Br)-OH is used in peptide synthesis, chemical biology research, and organic synthesis as a building block for creating modified peptides and complex molecules.

What is the CAS number and formula for Fmoc-Phe(4-Br)-OH?

The CAS number is 198561-04-5. The empirical formula is C24H20BrNO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Phe(4-Br)-OH with a purity of ≥98.0%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.

What are the safety considerations for handling Fmoc-Phe(4-Br)-OH?

Fmoc-Phe(4-Br)-OH is classified with hazard statement H413, indicating it may cause long lasting harmful effects to aquatic life. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter, should be used. Handle with care in a well-ventilated area.

How is Fmoc-Phe(4-Br)-OH packed and shipped?

Fmoc-Phe(4-Br)-OH is carefully packed to ensure stability during transit and is exported globally by TSS in compliance with all relevant shipping regulations.