Thiamine pyrophosphate
Thiamine pyrophosphate (CAS: 154-87-0), a biologically active form of thiamine, is a vital cofactor in numerous metabolic pathways, particularly carbohydrate metabolism. Its chemical formula is C12H19ClN4O7P2S and it has a molecular weight of 460.77 g/mol. This compound serves as a crucial substrate in enzymatic assays and plays a role in cellular energy production and nerve function, making it indispensable in biochemical research.
- IUPAC
- Aneurinepyrophosphoric acid,Cocarboxylase,Thiamine pyrophosphate chloride
- Synonyms
- Aneurinepyrophosphoric acidCocarboxylaseThiamine pyrophosphate chloride
Enzymatic Assays
Thiamine pyrophosphate is utilized as a substrate in biochemical assays to study enzyme activity, particularly those involved in thiamine metabolism. For example, it has been used to assay enzymes found in Golgi lamellae isolated from rat tissue.
Metabolic Research
As a key cofactor, it is essential for understanding carbohydrate metabolism and cellular energy production. Researchers use it to investigate pathways like the pentose phosphate pathway and the citric acid cycle.
Biochemical Studies
This compound is broadly applied in biochemical research to explore the function of thiamine-dependent enzymes and their role in various biological processes, including neurotransmitter synthesis.
| Molecular weight | 460.77 |
|---|---|
| Empirical formula | C12H19ClN4O7P2S |
| Assay | ≥95% |
| Solubility | H2O: soluble50 mg/mL, clear to very slightly hazy, colorless |
| Storage temperature | −20°C |
| Application | Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thiamine pyrophosphate used for?
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Thiamine pyrophosphate is primarily used as a substrate in enzymatic assays and for research into metabolic pathways, particularly carbohydrate metabolism and cellular energy production.
What is the CAS number and chemical formula for Thiamine pyrophosphate?
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The CAS number for Thiamine pyrophosphate is 154-87-0, and its chemical formula is C12H19ClN4O7P2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Thiamine pyrophosphate with an assay of ≥95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Thiamine pyrophosphate be handled and stored?
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Handle Thiamine pyrophosphate with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) is recommended. Store at -20°C. The WGK Germany is 3.
Is Thiamine pyrophosphate a controlled substance?
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The provided data does not indicate that Thiamine pyrophosphate is a controlled substance.
How is Thiamine pyrophosphate packed, shipped, and exported?
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Tech Serve Solutions can provide Thiamine pyrophosphate in various quantities, suitable for laboratory research and bulk export, adhering to all necessary shipping regulations for chemical compounds.
How can I request a sample or quote for Thiamine pyrophosphate?
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To request a sample or a quote for Thiamine pyrophosphate, please contact our sales team through the TSS website or by calling our customer service line.
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