Theophylline
Theophylline (CAS: 58-55-9, C7H8N4O2, MW: 180.16) is a methylxanthine compound. It occurs as a white crystalline powder and is primarily recognised for its bronchodilator properties, making it a key component in managing respiratory conditions like asthma and COPD. Beyond its pharmaceutical significance, it also finds applications as a biochemical reagent in scientific research, particularly in enzyme inhibition studies.
- IUPAC
- 1,3-Dimethylxanthine,2,6-Dihydroxy-1,3-dimethylpurine,3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- Synonyms
- 1,3-Dimethylxanthine2,6-Dihydroxy-1,3-dimethylpurine3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
Pharmaceutical Intermediate
Theophylline is a vital precursor and active pharmaceutical ingredient used in the formulation of bronchodilator medications. It aids in relaxing airway muscles, easing breathing difficulties associated with conditions such as asthma and chronic obstructive pulmonary disease (COPD).
Biochemical Research
As a methylxanthine derivative, theophylline is employed in laboratory settings as a biochemical reagent. Its known effects on cellular signalling pathways, including phosphodiesterase inhibition, make it a valuable tool for investigating enzyme activity and cellular responses.
Enzyme Inhibition Studies
The compound serves as an inhibitor in enzymatic research. Scientists utilise theophylline to study the mechanisms of various enzymes, particularly phosphodiesterases, by observing the effects of its inhibitory action on biological processes.
| Molecular weight | 180.16 |
|---|---|
| Empirical formula | C7H8N4O2 |
| Assay | ≥99.0% (HPLC) |
| Loss on drying | ≤0.5% loss on drying |
| Melting point | 271-273 °C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Theophylline used for?
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Theophylline is primarily used in pharmaceuticals as a bronchodilator to treat respiratory conditions like asthma and COPD. It is also utilised in biochemical research as an enzyme inhibitor.
What are the CAS number and formula for Theophylline?
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The CAS number for Theophylline is 58-55-9, and its empirical formula (Hill notation) is C7H8N4O2.
What grade and purity does Tech Serve Solutions supply for Theophylline?
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Tech Serve Solutions supplies Theophylline with a purity of ≥99.0% (HPLC) and ≤0.5% loss on drying. This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
What are the key safety hazards associated with Theophylline?
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Theophylline is classified with GHS06 symbol and the signal word 'Danger'. It carries the hazard statement H301 (Toxic if swallowed). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, should be used when handling. Precautionary statement P301 + P310 indicates immediate medical attention if swallowed.
Is Theophylline a controlled substance?
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The provided safety data does not indicate that Theophylline (CAS: 58-55-9) is a controlled substance under standard regulations. However, regulations can vary by jurisdiction and intended use.
How is Theophylline packed and exported by TSS?
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Theophylline is shipped according to UN 2811 6.1 / PGIII classification. TSS, as a global supplier and exporter, adheres to all relevant shipping and handling regulations for chemical products.
How can I request a sample or quote for Theophylline?
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To request a sample or a quote for Theophylline, please contact the Tech Serve Solutions sales team through our website or your designated representative.
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