Thiamphenicol

CAS 15318-45-3C12H15Cl2NO5SBiochemicals & Reagents

Thiamphenicol (CAS: 15318-45-3), a synthetic antibiotic with the molecular formula C12H15Cl2NO5S and a molecular weight of 356.22 g/mol, is employed in scientific research. It functions by inhibiting bacterial protein synthesis. Primarily used in laboratory settings for studies related to antibiotic resistance mechanisms and the analysis of ribosomal function, Thiamphenicol is a valuable tool for biochemical and microbiological investigations.

IUPAC: D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide

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Thiamphenicol (C12H15Cl2NO5S) — chemical structure, CAS 15318-45-3; Life Science, fine chemical supplied by Tech Serve Solutions

AntibacterialAntibioticsAntibiotics A to ZAntibiotics T-ZBiochemicals and ReagentsChemical Structure ClassMechanism of ActionPhenicolesSpectrum of Activity More...

01 /Applications

Antibacterial Research

Thiamphenicol serves as a research tool to study mechanisms of bacterial protein synthesis inhibition, particularly its interaction with the 23S rRNA of the 50S ribosomal subunit.

Antibiotic Resistance Studies

Used in investigations into chloramphenicol-thiamphenicol resistance and the efficacy of fluorinated analogues when resistance is encountered.

Biochemical Investigations

Applied in biochemical research to understand the peptidyl transferase activity associated with ribosomal function and antibiotic action.

02 /Properties

Molecular weight	356.22
Empirical formula	C12H15Cl2NO5S
Application	Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea1,2. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered3.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

15318-45-3

MDL number

MFCD00467983

Beilstein registry

2819542

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Thiamphenicol used for?

Thiamphenicol is used in scientific research to study bacterial protein synthesis and antibiotic resistance mechanisms, particularly involving ribosomal function.

What are the CAS number and formula for Thiamphenicol?

The CAS number for Thiamphenicol is 15318-45-3, and its molecular formula is C12H15Cl2NO5S.

What grade and purity does Tech Serve Solutions supply for Thiamphenicol?

Tech Serve Solutions supplies Thiamphenicol typically as a technical or research grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated in the product's specifications. Please refer to the product's Certificate of Analysis for precise assay information.

What are the safety considerations for handling Thiamphenicol?

Handling Thiamphenicol requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, due to its classification with WGK Germany 2.

How is Thiamphenicol packed, shipped, and exported?

Tech Serve Solutions provides comprehensive packing, shipping, and export services for Thiamphenicol, adhering to all relevant regulations for chemical handling and international trade.

How can I request a sample or quote for Thiamphenicol?

To request a sample or quote for Thiamphenicol, please contact our sales team through the website or by phone, providing your contact details and the quantity required.