Thio-TEPA
Thio-TEPA (CAS 52-24-4), with the molecular formula C6H12N3PS, is a chemical compound employed as an alkylating agent in cancer chemotherapy. It is recognised for its application in treating various malignancies, including breast, ovarian, and bladder cancers. Furthermore, it serves as a conditioning regimen prior to haematopoietic progenitor cell transplantation. Stored under refrigerated conditions (2-8°C), this solid compound is available at 98% purity.
- IUPAC
- N,N′,N″-Triethylenethiophosphoramide,Thio-Tep,Thiofozil,Thiotef,Tio-tef,Tiofosfamid,Tiofosyl,Tiofozil,Tris(aziridinyl)phosphine sulfide
- Synonyms
- N,N′,N″-TriethylenethiophosphoramideThio-TepThiofozilThiotefTio-tefTiofosfamidTiofosylTiofozilTris(aziridinyl)phosphine sulfide
Cancer Chemotherapy
Thio-TEPA is utilised as a chemotherapeutic agent for its alkylating properties. It is prescribed in the treatment protocols for several types of cancer.
Malignancy Treatment
The compound is specifically indicated for treating cancers such as breast, ovarian, and bladder cancer, acting to disrupt cancer cell proliferation.
Haematopoietic Progenitor Cell Transplantation
Thio-TEPA functions as a conditioning treatment before patients undergo haematopoietic progenitor cell transplantation (HPCT).
| Molecular weight | 189.22 |
|---|---|
| Empirical formula | C6H12N3PS |
| Assay | 98% |
| Form | solid |
| Storage temperature | 2-8°C |
| Application | Thio-TEPA (N,N’N’-triethylenethiophosphoramide) is used as a cancer chemotherapeutic, alkylating agent. It is used to treat various kinds of cancer such as breast, ovarian and bladder cancer. It is also used as conditioning treatment prior to haematopoietic progenitor cell transplantation (HPCT)1,2. |
Hazard statements
- H300Fatal if swallowed
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 45-46-28 |
| Safety statements (S) | 53-22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thio-TEPA used for?
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Thio-TEPA is used as a cancer chemotherapeutic, alkylating agent for treating various cancers like breast, ovarian, and bladder cancer, and as a conditioning treatment prior to haematopoietic progenitor cell transplantation.
What are the CAS number and formula for Thio-TEPA?
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The CAS number for Thio-TEPA is 52-24-4, and its empirical formula is C6H12N3PS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Thio-TEPA with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should Thio-TEPA be handled safely?
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Thio-TEPA is a Danger hazard substance (H300, H350). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection. Consult the safety data sheet for comprehensive guidance.
How is Thio-TEPA packed and shipped?
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Thio-TEPA is typically packed as a solid and shipped according to regulations for hazardous materials, requiring specific handling procedures. International export services are available.
How can I request a quote or sample of Thio-TEPA?
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To request a quote or sample, please contact our sales department via the website or direct inquiry, providing your specific requirements.
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