Thioperamide maleate salt
Thioperamide maleate salt (CAS 148440-81-7) is a chemical compound with the formula C15H24N4S · C4H4O4 and a molecular weight of 408.52 g/mol. This white solid is primarily utilized in scientific research for its role as an antagonist, particularly in studying sympathetic and autonomic nerve activity in mammalian white adipose tissue. Its specific properties make it a valuable tool for investigations in cell biology, neuroscience, and GPCR modulation.
- IUPAC
- MR-12842,N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide maleate salt

Adipose Tissue Research
Thioperamide maleate salt has been employed to investigate the functional roles of the sympathetic and autonomic nervous systems in mammalian white adipose tissue. This allows researchers to explore mechanisms related to energy metabolism and thermogenesis.
Neuroscience and Cell Signaling Studies
As a GPCR modulator and antagonist, this compound serves as a valuable tool in neuroscience research. It aids in understanding neurotransmission pathways and cellular signaling cascades, particularly those involving histamine receptors.
Biochemical and Reagent Applications
The compound's well-defined properties make it suitable for various biochemical assays and as a reagent in cell biology studies. Its use helps in elucidating complex biological processes at the molecular level.
| Molecular weight | 408.52 |
|---|---|
| Empirical formula | C15H24N4S · C4H4O4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: >10 mg/mLDMSO: soluble12 mg/mLethanol: soluble3 mg/mL |
| Application | Thioperamide maleate salt was used to study the sympathetic1 and autonomic2 nerve activity in mammalian white adipose tissue. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HRH3(11255) |
|---|---|
| Storage Condition | desiccatedunder inert gas |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thioperamide maleate salt used for?
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Thioperamide maleate salt is used in scientific research, particularly for studying sympathetic and autonomic nerve activity in mammalian white adipose tissue, and in neuroscience and cell signaling investigations as a GPCR modulator.
What are the CAS number and formula for Thioperamide maleate salt?
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The CAS number for Thioperamide maleate salt is 148440-81-7, and its formula is C15H24N4S · C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Thioperamide maleate salt with an assay of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for Thioperamide maleate salt?
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Thioperamide maleate salt is classified as a Warning, with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves should be used. Handle in a well-ventilated area or under an inert gas, and store desiccated.
How is Thioperamide maleate salt packed, shipped, and exported?
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Thioperamide maleate salt is typically packed as a white solid, stored desiccated under inert gas. As a global supplier, Tech Serve Solutions can export this chemical worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for Thioperamide maleate salt?
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To request a sample or a quote for Thioperamide maleate salt, please contact our sales department via the website or by phone. Our team will be pleased to assist you with your research chemical needs.
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