Thiostrepton from Streptomyces azureus

CAS 1393-48-2C72H85N19O18S5Biochemicals & Reagents

Thiostrepton from Streptomyces azureus (CAS: 1393-48-2), a complex thiopeptide antibiotic with the formula C72H85N19O18S5 and molecular weight 1664.89 g/mol, is supplied by Tech Serve Solutions. Primarily recognized for its potent antibacterial properties, it serves as a critical selectable marker in genetic research, particularly for Streptomyces cultures. This compound is essential for molecular biology and biochemical applications requiring precise control over microbial gene expression and selection.

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Thiostrepton from Streptomyces azureus (C72H85N19O18S5) — chemical structure, CAS 1393-48-2; Life Science, fine chemical supplied by Tech Serve Solutions

AntibacterialAntibioticsAntibiotics A to ZAntibiotics T-ZAntibiotics by ApplicationBioactive Small MoleculesBiochemicals and ReagentsCell BiologyChemical Structure ClassGenetic Marker Selection

01 /Applications

Selectable Marker in Streptomyces

Thiostrepton is employed as a highly effective selectable marker for the selection of recombinant Streptomyces strains in molecular biology research. Its use facilitates the identification and isolation of genetically modified microorganisms.

Antibacterial Research

As a naturally occurring thiopeptide antibiotic, Thiostrepton is valuable in studies investigating antibacterial mechanisms and the development of novel antimicrobial agents. Its specific mode of action, interfering with protein synthesis, makes it a target for research.

Biochemical and Reagent Applications

This compound functions as a biochemical reagent in cell biology and related fields. Researchers utilise it in experiments concerning gene regulation, protein synthesis inhibition, and cellular processes.

02 /Properties

Molecular weight	1664.89
Empirical formula	C72H85N19O18S5
Assay	≥90% (HPLC)
Solubility	acetic acid: soluble25 mg/mL, clear to hazy, yellow to brownish-yellow
Storage temperature	−20°C
Application	Thiostrepton has been used as a selectable marker for recombinant Streptomyces cultures1,2,3.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1393-48-2

MDL number

MFCD00135828

PubChem substance

24900569

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Thiostrepton used for?

Thiostrepton is primarily used as a selectable marker for recombinant Streptomyces cultures and in antibacterial research due to its ability to interfere with protein synthesis.

What is the CAS number and formula for Thiostrepton?

The CAS number for Thiostrepton is 1393-48-2, and its empirical formula is C72H85N19O18S5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Thiostrepton with an assay of ≥90% by HPLC. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.

How should Thiostrepton be handled safely?

Thiostrepton is harmful if swallowed (H302). When handling, it is essential to wear appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter.

How is Thiostrepton shipped and exported?

Tech Serve Solutions, as a global supplier, exports and ships Thiostrepton under appropriate conditions, including storage at -20°C, ensuring product integrity during transit.