(R)-2-(Aminomethyl)-1-Boc-pyrrolidine
(R)-2-(Aminomethyl)-1-Boc-pyrrolidine (CAS: 259537-92-3, C10H20N2O2) is a chiral building block with a molecular weight of 200.28. This Boc-protected pyrrolidine derivative is valuable in asymmetric synthesis and heterocyclic chemistry. It serves as a key intermediate for constructing complex chiral molecules, particularly in the development of pharmaceuticals and other fine chemicals where specific stereochemistry is crucial for biological activity.
- IUPAC
- (R)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine,tert-Butyl (R)-2-(aminomethyl)-1-pyrrolidinecarboxylate
- Synonyms
- tert-Butyl (R)-2-(aminomethyl)-1-pyrrolidinecarboxylate
Chiral Building Block in Asymmetric Synthesis
This compound is utilized as a chiral precursor in enantioselective synthesis. Its pyrrolidine ring and protected amine functionality allow for stereocontrolled introduction of substituents, leading to the creation of optically pure target molecules.
Pharmaceutical Intermediate
It serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). The chiral nature of the molecule is often essential for the efficacy and specificity of drug candidates targeting various therapeutic areas.
Heterocyclic Chemistry
The Boc-protected pyrrolidine structure makes it a useful reagent in the synthesis of complex heterocyclic compounds. These heterocycles are prevalent scaffolds in medicinal chemistry and materials science.
| Molecular weight | 200.28 |
|---|---|
| Empirical formula | C10H20N2O2 |
| Assay | ≥97.5% (GC)98% |
| Optical activity | [α]/D +47.0±2°, c = 1 in chloroform |
| Optical purity | enantiomeric excess: ≥99.0% |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C,N |
| Risk statements (R) | 22-34-51/53 |
| Safety statements (S) | 26-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-2-(Aminomethyl)-1-Boc-pyrrolidine used for?
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(R)-2-(Aminomethyl)-1-Boc-pyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the production of pharmaceuticals and other complex organic molecules.
What is the CAS number and chemical formula for (R)-2-(Aminomethyl)-1-Boc-pyrrolidine?
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The CAS number is 259537-92-3 and the empirical formula is C10H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-2-(Aminomethyl)-1-Boc-pyrrolidine with an assay of ≥97.5% (GC) or 98%, and an enantiomeric excess of ≥99.0%. This product is intended for research and chemical synthesis; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
How should (R)-2-(Aminomethyl)-1-Boc-pyrrolidine be handled and stored?
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This compound is classified as Danger, with hazards H302 (Harmful if swallowed) and H314 (Causes severe skin burns and eye damage). It requires careful handling with appropriate personal protective equipment, including face shields, gloves, and respirators. Store at 2-8°C in a well-ventilated area.
Is (R)-2-(Aminomethyl)-1-Boc-pyrrolidine a controlled substance?
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The provided data does not indicate that (R)-2-(Aminomethyl)-1-Boc-pyrrolidine is a scheduled or controlled substance.
How can I request a sample or quote for (R)-2-(Aminomethyl)-1-Boc-pyrrolidine?
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To request a sample or obtain a quote, please contact our sales team through the website or by phone. Provide the product name and CAS number for prompt service.
How is (R)-2-(Aminomethyl)-1-Boc-pyrrolidine packed and exported?
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This chemical is classified under UN 2735, Class 8, PG 3. It is carefully packed according to international shipping regulations for hazardous materials and exported globally by TSS.
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