(R)-1-{(SP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine
(R)-1-{(SP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS: 849924-41-0, Formula: C28H36FeO2P2, MW: 522.38) is a specialized organometallic compound widely recognised as a privileged chiral ligand. Its unique structure, featuring a ferrocene backbone and bulky phosphine groups, makes it highly effective in catalysing asymmetric transformations. This compound is instrumental in the synthesis of enantiomerically pure molecules, particularly within the pharmaceutical and fine chemical industries, enabling precise control over stereochemistry in complex reactions.
- IUPAC
- (2R)-1-[(1R)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(di-2-furanylphosphino)ferrocene (acc to CAS),Josiphos SL-J212-1
![(R)-1-{(SP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (C28H36FeO2P2) — chemical structure, CAS 849924-41-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-41-0.png&w=3840&q=75)
Asymmetric Catalysis
This chiral phosphine ligand is extensively employed in transition metal-catalysed asymmetric reactions. It facilitates high enantioselectivity in processes such as asymmetric hydrogenation, cross-coupling reactions, and conjugate additions, crucial for producing enantiopure active pharmaceutical ingredients (APIs).
Pharmaceutical Synthesis
Its application in the synthesis of complex chiral molecules makes it invaluable for the pharmaceutical industry. By enabling the efficient and selective formation of specific stereoisomers, it supports the development and manufacturing of novel drug candidates.
Fine Chemical Manufacturing
In the fine chemical sector, this ligand is utilised for producing high-value chiral intermediates. Its reliability and effectiveness in stereoselective synthesis contribute to the production of specialised chemicals with demanding purity requirements.
Organometallic Chemistry Research
As a sophisticated Josiphos-type ligand, it is a subject of study in organometallic and catalysis research. Its versatile coordination chemistry and application in challenging catalytic cycles are of significant academic and industrial interest.
| Molecular weight | 522.38 |
|---|---|
| Empirical formula | C28H36FeO2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-{(SP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis for the synthesis of enantiomerically pure compounds, particularly in the pharmaceutical and fine chemical industries. It is effective in various transition metal-catalysed reactions requiring high stereoselectivity.
What are the CAS number and formula for this chemical?
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The CAS number is 849924-41-0 and the empirical formula is C28H36FeO2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and optical purity of ee: ≥99%. This is a research-grade chemical and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should this chemical be handled and stored?
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Handle with appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Store in a cool, dry, well-ventilated area, away from incompatible substances. Note that the WGK Germany is 3, indicating a higher hazard level.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product, serving customers worldwide.
How can I request a quote or sample?
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To request a quote or a sample of (R)-1-{(SP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine, please visit the product page on the Tech Serve Solutions website and use the designated inquiry form or contact our sales team directly.
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