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(R)-1-{(SP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine

CAS 851308-40-2C48H44FeP2Chemical Synthesis

(R)-1-{(SP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine, CAS 851308-40-2, is a sophisticated organometallic compound with a molecular weight of 738.66 g/mol. As a member of the Josiphos ligand family, it is specifically designed for highly enantioselective catalytic applications, particularly in asymmetric synthesis. This advanced phosphine ligand is crucial for achieving high stereoselectivity in various organic transformations.

IUPAC
(2R)-1-[(1R)-1-[Bis(3,5-dimethylphenyl)phosphino]ethyl]-2-(di-1-naphthalenylphosphino)ferrocene (acc to CAS),Josiphos SL-J404-1
Synonyms
C48H44FeP2(2R)-1-[(1R)-1-[Bis(3,5-dimethylphenyl)phosphino]ethyl]-2-(di-1-naphthalenylphosphino)ferroceneJosiphos SL-J404-1
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(R)-1-{(SP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine (C48H44FeP2) — chemical structure, CAS 851308-40-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsJosiphos Ligands
01 /Applications

Asymmetric Catalysis

This compound functions as a highly effective chiral ligand in transition metal catalysis, facilitating enantioselective transformations. It is particularly useful in reactions such as asymmetric hydrogenation, cross-coupling, and conjugate addition.

Pharmaceutical Intermediate Synthesis

Its ability to control stereochemistry makes it invaluable for the synthesis of chiral pharmaceutical intermediates, where precise enantiomeric purity is critical for drug efficacy and safety.

Fine Chemical Production

The ligand is employed in the production of complex fine chemicals, enabling the efficient and stereoselective synthesis of target molecules with specific chiral centres.

02 /Properties
Molecular weight738.66
Empirical formulaC48H44FeP2
Assay≥97%
Optical purityee: ≥99%
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
851308-40-2
MDL number
MFCD08561162
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-1-{(SP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine used for?

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(R)-1-{(SP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine is primarily used as a chiral ligand in asymmetric catalysis for enantioselective synthesis, particularly in the production of pharmaceutical intermediates and fine chemicals.

What is the CAS number and formula for this compound?

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The CAS number is 851308-40-2, and the empirical formula is C48H44FeP2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this compound with an assay of ≥97% and an optical purity (ee) of ≥99%. We do not represent this product as USP, BP, or EP grade.

What are the safety and handling considerations?

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This compound is classified with WGK Germany 3. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling.

How is this chemical packed, shipped, and exported?

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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, ensuring appropriate packaging and compliance for international shipment.

How can I request a sample or quote?

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Please contact Tech Serve Solutions directly through our website or sales department to request a sample or a quotation for (R)-1-{(SP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine.

Need (R)-1-{(SP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine in a specific grade or volume?