(R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine
(R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine (CAS 166172-63-0) is a high-purity organometallic compound with a molecular weight of 910.53 g/mol. As a key chiral ligand, it is instrumental in asymmetric synthesis, facilitating the creation of enantiomerically pure compounds. Its specific structure makes it highly effective in various catalytic applications within chemical synthesis, particularly where stereochemical control is paramount.
- IUPAC
- (1R)-1-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]-2-[(1R)-1-[bis(3,5-dimethylphenyl)phosphino]ethyl]ferrocene (acc to CAS),Josiphos SL-J008-1
- Synonyms
- 166172-63-0C44H36F12FeP2Josiphos SL-J008-1
![(R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine (C44H36F12FeP2) — chemical structure, CAS 166172-63-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F166172-63-0.png&w=3840&q=75)
Asymmetric Catalysis
This compound serves as a sophisticated chiral ligand in transition metal catalysis, enabling highly enantioselective transformations. It is particularly effective in reactions requiring precise stereochemical control for the synthesis of complex molecules.
Organometallic Synthesis
It is employed in advanced organometallic synthesis, leveraging its unique ferrocenyl backbone and phosphine substituents. This enables the construction of complex molecular architectures with defined stereochemistry.
Pharmaceutical Intermediate Synthesis
The high enantiomeric purity achievable with this ligand makes it valuable in the synthesis of chiral pharmaceutical intermediates. It aids in producing single enantiomers of active pharmaceutical ingredients (APIs).
| Molecular weight | 910.53 |
|---|---|
| Empirical formula | C44H36F12FeP2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi(3,5-xylyl)phosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and organometallic catalysis, particularly for creating enantiomerically pure compounds and pharmaceutical intermediates.
What are the CAS number and formula for this compound?
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The CAS number is 166172-63-0, and its empirical formula (Hill notation) is C44H36F12FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97% and an optical purity of ee: ≥99%. It is supplied as a technical/research grade and is not represented as USP/BP/EP.
What are the safety precautions for handling this chemical?
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When handling this chemical, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified with a WGK Germany of 3, indicating a high hazard level.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions ensures secure and compliant packing for domestic and international shipments, adhering to all relevant regulations for the export of fine chemicals.
How can I request a sample or quote for this product?
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To request a sample or obtain a quote, please contact our sales team through the website or by calling our direct line. Please reference the product name and CAS number.
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