(R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldicyclohexylphosphine
(R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldicyclohexylphosphine (CAS: 292638-88-1) is a highly effective chiral ferrocenylphosphine ligand utilized in asymmetric synthesis. With a molecular formula of C40H40F12FeP2 and a molecular weight of 866.52 g/mol, this compound is indispensable for stereoselective catalytic reactions. It plays a crucial role in the synthesis of complex chiral molecules, particularly in pharmaceutical and fine chemical research and development.
- IUPAC
- (1R)-1-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]-2-[(1R)-1-(dicyclohexylphosphino)ethyl]ferrocene (acc to CAS),Josiphos SL-J006-1
- Synonyms
- C40H40F12FeP2
![(R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldicyclohexylphosphine (C40H40F12FeP2) — chemical structure, CAS 292638-88-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F292638-88-1.png&w=3840&q=75)
Asymmetric Catalysis
This ligand is employed as a crucial component in transition metal catalysts for enantioselective transformations, enabling the synthesis of single enantiomers with high optical purity. It is particularly effective in reactions such as hydrogenation, hydroformylation, and cross-coupling.
Pharmaceutical Intermediate Synthesis
Its ability to control stereochemistry makes it invaluable in the multi-step synthesis of chiral active pharmaceutical ingredients (APIs) and their intermediates. This facilitates the production of enantiomerically pure drugs.
Chiral Ligand for Metal Complexes
As a sophisticated bidentate phosphine ligand, it forms highly active and selective chiral complexes with various transition metals. These complexes serve as powerful tools for stereoselective synthesis in organic chemistry.
Fine Chemical Production
The ligand is instrumental in the development and production of high-value fine chemicals where specific stereoisomers are required for their intended properties and applications.
| Molecular weight | 866.52 |
|---|---|
| Empirical formula | C40H40F12FeP2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldicyclohexylphosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis for enantioselective synthesis, particularly in the pharmaceutical and fine chemical industries.
What is the CAS number and formula for this compound?
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The CAS number is 292638-88-1 and the empirical formula is C40H40F12FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity (ee) of ≥99%. This product is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this chemical?
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Handle with appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK Germany rating of 3, indicating it is hazardous.
How is this product packed and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling packaging and shipping in compliance with international regulations for hazardous materials.
How can I request a quote or sample?
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Please contact our sales team through the website to request a quote or a sample of (R)-1-{(SP)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldicyclohexylphosphine.
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