(R)-1-{(SP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine
(R)-1-{(SP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS 246231-79-8) is a highly effective chiral ferrocenyl phosphine ligand. With the molecular formula C34H38F6FeP2 and a molecular weight of 678.45 g/mol, it is a key component in asymmetric catalysis. This advanced chemical is primarily utilised in stereoselective synthesis to control the formation of specific enantiomers in organic reactions, enabling the production of complex chiral molecules.
- IUPAC
- (2R)-1-[(1R)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-[bis[4-(trifluoromethyl)phenyl]phosphino]ferrocene (acc to CAS),Josiphos SL-J011-1
![(R)-1-{(SP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine (C34H38F6FeP2) — chemical structure, CAS 246231-79-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F246231-79-8.png&w=3840&q=75)
Asymmetric Hydrogenation
This ferrocenyl phosphine ligand is widely employed as a catalyst or pre-catalyst in asymmetric hydrogenation reactions. It enables the enantioselective reduction of various unsaturated substrates, yielding chiral alcohols, amines, and other valuable synthetic intermediates.
Cross-Coupling Reactions
It serves as a privileged ligand in various transition metal-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Buchwald-Hartwig aminations. Its unique electronic and steric properties facilitate high catalytic activity and selectivity in forming carbon-carbon and carbon-heteroatom bonds.
Chiral Ligand in Organometallic Catalysis
The compound functions as a sophisticated chiral ligand, imparting stereochemical control in a broad range of organometallic catalytic transformations. Its design facilitates efficient enantioselectivity and high turnover numbers in complex synthetic pathways.
| Molecular weight | 678.45 |
|---|---|
| Empirical formula | C34H38F6FeP2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-{(SP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and organometallic catalysis, particularly for enantioselective hydrogenation and cross-coupling reactions.
What are the CAS number and formula for this chemical?
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The CAS number is 246231-79-8, and its empirical formula is C34H38F6FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97% and an optical purity (ee) of ≥99%. It is supplied as a research-grade chemical and not represented as USP, BP, or EP grade.
How should this chemical be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store in a cool, dry place, away from incompatible materials, following standard laboratory safety protocols.
Is this compound a controlled substance?
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The provided data indicates a WGK Germany classification of 3, suggesting it requires careful handling and disposal but does not explicitly state it is a controlled substance under international regulations.
How is this product packed and shipped?
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Tech Serve Solutions ensures secure packing for global export, adhering to all necessary regulations for the safe transportation of fine chemicals.
How can I request a quote or sample?
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Please contact our sales team directly via the website or telephone to request a quotation or a sample for evaluation.
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