(R)-1-{(SP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine
(R)-1-{(SP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine (CAS 849924-49-8) is a sophisticated organophosphine ligand with the molecular formula C44H48FeO2P2 and a molecular weight of 726.64 g/mol. This chiral catalyst plays a crucial role in asymmetric synthesis, particularly in enantioselective transformations where high optical purity is paramount. It is widely employed in chemical synthesis for developing complex molecules and pharmaceutical intermediates.
- IUPAC
- (1R)-1-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]-2-[(1R)-1-[bis(2-methylphenyl)phosphino]ethyl]ferrocene (acc to CAS),Josiphos SL-J425-1
- Synonyms
- C44H48FeO2P2(1R)-1-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]-2-[(1R)-1-[bis(2-methylphenyl)phosphino]ethyl]ferroceneJosiphos SL-J425-1
![(R)-1-{(SP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine (C44H48FeO2P2) — chemical structure, CAS 849924-49-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-49-8.png&w=3840&q=75)
Asymmetric Catalysis
This compound functions as a chiral ligand in transition metal catalysis, enabling highly enantioselective reactions. Its unique structure facilitates the formation of specific stereoisomers, crucial for pharmaceutical development.
Pharmaceutical Intermediate Synthesis
It is instrumental in synthesising complex chiral molecules that serve as building blocks for active pharmaceutical ingredients (APIs). The high optical purity achieved aids in producing safer and more effective drugs.
Ligand for Homogeneous Catalysis
As a Josiphos-type ligand, it is a key component in various homogeneous catalytic systems, offering high activity and selectivity in cross-coupling and hydrogenation reactions.
| Molecular weight | 726.64 |
|---|---|
| Empirical formula | C44H48FeO2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-{(SP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, particularly in the development of pharmaceutical intermediates, offering high enantioselectivity in chemical transformations.
What is the CAS number and chemical formula for this product?
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The CAS number is 849924-49-8 and the empirical formula is C44H48FeO2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity of ee: ≥99%. This is a research grade chemical and is not represented as USP, BP, EP, or food grade.
What are the safety and handling considerations for this chemical?
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This compound is classified with WGK Germany of 3. Appropriate personal protective equipment, including eyeshields and gloves, is required. A type N95 (US) or type P1 (EN143) respirator filter should be used when handling.
How are your products packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents, ensuring secure and compliant packaging for international transit.
How can I request a sample or a quote for this product?
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Please contact our sales team directly via our website or by phone to request a sample or a formal quotation for this product.
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