5-[(3aR,8aR)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-5H-dibenz[b,f]azepine
5-[(3aR,8aR)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-5H-dibenz[b,f]azepine (CAS: 1092695-14-1) is a chiral phosphine-olefin ligand with a molecular weight of 687.76 g/mol. This complex molecule is a valuable tool in asymmetric synthesis, primarily utilised in rhodium-catalysed 1,4-addition reactions. Its sophisticated structure enables high enantioselectivity in various chemical transformations.
- IUPAC
- (3aR,8aR)-(−)-N-(2,2-Dimethyl-6-phospha-1,3,5,7-tetraoxa-4,4,8,8-tetraphenylbicyclo[3.5.0]decan-6-yl)dibenzo[b,f]azepine,N-[(1R,7R)-9,9-Dimethyl-2,2,6,6-tetraphenyl-3,5,8,10-tetraoxa-4-phosphabicyclo[5.3.0]decan-4-yl]dibenzo[b,f]azepine
- Synonyms
- 4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-5H-dibenz[b,f]azepine, C45H38NO4P, (3aR,8aR)-(−)-N-(2,2-Dimethyl-6-phospha-1,3,5,7-tetraoxa-4,4,8,8-tetraphenylbicyclo[3.5.0]decan-6-yl)dibenzo[b,f]azepine, N-[(1R,7R)-9,9-Dimethyl-2,2,6,6-tetraphenyl-3,5,8,10-tetraoxa-4-phosphabicyclo[5.3.0]decan-4-yl]dibenzo[b,f]azepine
![5-[(3aR,8aR)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-5H-dibenz[b,f]azepine (C45H38NO4P) — chemical structure, CAS 1092695-14-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1092695-14-1.png&w=3840&q=75)
Asymmetric 1,4-Addition Reactions
This phosphine-olefin ligand is employed in rhodium-catalysed asymmetric 1,4-addition reactions. It facilitates the enantioselective addition of nucleophiles to activated alkenes, a critical step in synthesising chiral molecules.
Chiral Catalyst Development
Its unique structure makes it a useful component in the development of novel chiral catalysts. These catalysts are essential for producing enantiomerically pure compounds for pharmaceuticals and fine chemicals.
Ligand for Transition Metal Catalysis
The compound serves as a privileged ligand in transition metal catalysis, particularly with rhodium. It can influence the stereochemical outcome of catalytic processes, enabling the synthesis of specific enantiomers.
| Molecular weight | 687.76 |
|---|---|
| Empirical formula | C45H38NO4P |
| Assay | ≥97% (elemental analysis)97% |
| Application | Versatile chiral phosphine-olefin ligand. Used in rhodium catalyzed asymmetric 1,4-additions1,2. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-[(3aR,8aR)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-5H-dibenz[b,f]azepine used for?
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This compound is primarily used as a chiral phosphine-olefin ligand in rhodium-catalysed asymmetric 1,4-addition reactions to synthesise enantiomerically enriched products.
What is the CAS number and chemical formula?
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The CAS number is 1092695-14-1, and the empirical formula is C45H38NO4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97% (elemental analysis) and 97%. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations?
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This substance is classified with a WGK (Germany) of 3, indicating it is hazardous to water. Appropriate personal protective equipment should be worn, and it should be handled in a well-ventilated area away from incompatible materials.
How is this chemical packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions expertly packs and exports fine chemicals worldwide, adhering to all relevant international shipping and customs regulations.
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales team through the website or direct email, providing the product name and CAS number (1092695-14-1).
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