5-[(Trimethylsilyl)ethynyl])-1-methylimidazole
5-[(Trimethylsilyl)ethynyl]-1-methylimidazole (CAS: 480439-45-0), with the molecular formula C9H14N2Si and a molecular weight of 178.31 g/mol, is a specialised heterocyclic building block. This compound is primarily utilised in chemical synthesis and research laboratories. Its structure, featuring an imidazole ring functionalised with a trimethylsilyl-protected ethynyl group, makes it a versatile intermediate for creating more complex organic molecules.
![5-[(Trimethylsilyl)ethynyl])-1-methylimidazole (C9H14N2Si) — chemical structure, CAS 480439-45-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480439-45-0.png&w=3840&q=75)
Organic Synthesis Intermediate
Serves as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry and materials science due to the imidazole and alkyne functionalities.
Research and Development
Employed in R&D settings for the exploration of novel chemical entities and reaction pathways. Its specific structure allows for targeted derivatisation.
Heterocyclic Chemistry
Valuable in the field of heterocyclic chemistry for constructing molecules that incorporate the imidazole motif, which is prevalent in many biologically active compounds.
| Molecular weight | 178.31 |
|---|---|
| Empirical formula | C9H14N2Si |
| Assay | 98% |
| Melting point | 55-59 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-[(Trimethylsilyl)ethynyl]-1-methylimidazole used for?
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This compound is primarily used as a building block in organic synthesis and in research and development for creating complex organic molecules, especially within heterocyclic and medicinal chemistry.
What are the CAS number and formula for 5-[(Trimethylsilyl)ethynyl]-1-methylimidazole?
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The CAS number is 480439-45-0 and the empirical formula is C9H14N2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98%. It is supplied as a technical or research grade material and is not represented as USP, BP, or EP grade.
How should 5-[(Trimethylsilyl)ethynyl]-1-methylimidazole be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash skin thoroughly after handling. Ensure good ventilation. This compound is a Warning with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
Is 5-[(Trimethylsilyl)ethynyl]-1-methylimidazole a controlled substance?
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The provided data does not indicate that 5-[(Trimethylsilyl)ethynyl]-1-methylimidazole is a controlled substance.
How is this chemical packed and shipped?
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Tech Serve Solutions securely packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally.
How can I request a sample or quote for this chemical?
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Please contact the Tech Serve Solutions sales team directly to request a sample or a formal quotation for 5-[(Trimethylsilyl)ethynyl]-1-methylimidazole.
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