SKI 5C
SKI 5C (CAS: 120005-55-2, C26H45NO4) is a chemical compound supplied by Tech Serve Solutions. This substance is presented as a colorless to light brown oil with a purity of ≥98% (HPLC). SKI 5C is primarily utilised in biochemical research for its role as an inhibitor in cell signalling pathways, specifically targeting Sphingosine Kinase 1.
- IUPAC
- 2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethyl ester-3-oxazolidinecarboxylic acid,SPHK1 Inhibitor 5C
- Synonyms
- SPHK1 Inhibitor 5C2,2-Dimethyl-4S-(1-oxo-2-hexadecyn-1-yl)-1,1-dimethylethyl ester-3-oxazolidinecarboxylic acid

Sphingosine Kinase 1 Inhibition
SKI 5C serves as a research tool to inhibit Sphingosine Kinase 1 (SK1). It has been employed in cellular studies, such as in SK-Hep1 and HEK-293T cells, to investigate the role of SK1 in various biological processes.
Cell Signaling Research
As an inhibitor of sphingosine kinase, SKI 5C is valuable for exploring the complex mechanisms of cell signalling pathways. Its application aids in understanding lipid-mediated signalling cascades relevant to cellular functions and potential disease mechanisms.
Neuroscience Investigations
Given its role in cell signalling, SKI 5C may be used in neuroscience research to study lipid signalling in neuronal cells. This can contribute to understanding the involvement of sphingosine kinases in neural development and function.
| Molecular weight | 435.64 |
|---|---|
| Empirical formula | C26H45NO4 |
| Assay | ≥98% (HPLC) |
| Form | oil |
| Colour | colorless to light brown |
| Storage temperature | 2-8°C |
| Application | SKI 5C was used to inhibit Sphingosine kinase 1 in SK-Hep1, HEK-293T cells.1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SKI 5C used for?
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SKI 5C is used in research as an inhibitor of Sphingosine Kinase 1 (SK1), aiding in the study of cell signalling pathways, particularly in cell biology, neuroscience, and kinase/phosphatase research.
What is the CAS number and molecular formula for SKI 5C?
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The CAS number for SKI 5C is 120005-55-2 and its molecular formula is C26H45NO4.
What grade and purity does Tech Serve Solutions supply for SKI 5C?
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Tech Serve Solutions supplies SKI 5C with a minimum purity of ≥98% (HPLC). This is a research-grade chemical and is not represented as USP, BP, EP, or pharmaceutical grade.
How should SKI 5C be stored and handled?
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SKI 5C should be stored at 2-8°C. It is classified under WGK Germany 3, indicating it is hazardous to water. Standard laboratory precautions for handling chemicals should be followed.
Is SKI 5C a controlled substance?
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The provided data does not indicate that SKI 5C is a controlled substance.
How can I request a sample or quote for SKI 5C?
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Please contact the Tech Serve Solutions sales team through our website or by phone to request a sample or obtain a quotation for SKI 5C.
How is SKI 5C typically supplied and exported?
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SKI 5C is supplied as an oil and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
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