SKF-96365
SKF-96365 (CAS: 130495-35-1), with the empirical formula C22H26N2O3 · HCl and a molecular weight of 402.91 g/mol, is a white solid. This compound is recognised as a calcium channel modulator and has been instrumental in research investigating the role of STIM1 protein in calcium influx mediated by calcium store depletion. It is primarily utilised in scientific research for its properties as a cell signaling and neuroscience research tool.
- IUPAC
- 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole,1-[β-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenethyl]-1H-imidazole hydrochloride
- Synonyms
- 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole,1-[β-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenethyl]-1H-imidazole hydrochloride
Calcium Channel Modulation Studies
SKF-96365 serves as a valuable tool in the study of calcium channel function. Its known modulatory effects allow researchers to investigate various physiological processes influenced by ion channel activity.
Investigation of STIM1 Protein Function
This compound was specifically employed in research to elucidate the role of the STIM1 protein in calcium (Ca2+)-store-depletion-mediated calcium influx, providing critical insights into cellular calcium homeostasis mechanisms.
Cell Signaling Research
As a bioactive small molecule, SKF-96365 is utilized in cell biology and neuroscience to probe complex cell signaling pathways. Its application aids in understanding the intricate mechanisms governing cellular communication and response.
| Molecular weight | 402.91 |
|---|---|
| Empirical formula | C22H26N2O3 · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >20 mg/mLH2O: >20 mg/mL |
| Application | SKF-96365 was used to study the role of STIM1 protein in Ca2+-store-depletion-mediated Ca2+ influx.3 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SKF-96365 used for?
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SKF-96365 is used in scientific research, particularly for studying the role of STIM1 protein in Ca2+-store-depletion-mediated Ca2+ influx, and as a calcium channel modulator in cell signaling and neuroscience research.
What is the CAS number and chemical formula for SKF-96365?
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The CAS number for SKF-96365 is 130495-35-1, and its chemical formula is C22H26N2O3 · HCl.
What grade and purity does Tech Serve Solutions supply for SKF-96365?
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Tech Serve Solutions supplies SKF-96365 with an assay of ≥98% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should SKF-96365 be handled safely?
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SKF-96365 is classified with GHS07 symbol and a Warning signal word, with hazard statements H315, H319, and H335. Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation. Avoid breathing dust and contact with skin and eyes.
Is SKF-96365 available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including SKF-96365, adhering to all necessary regulations for international shipment.
How can I request a quote or sample for SKF-96365?
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To request a quote or a sample of SKF-96365, please contact our sales department through the website or via direct inquiry, providing your specific requirements and shipping details.
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