1-Fmoc-3-oxopiperazine
1-Fmoc-3-oxopiperazine (CAS: 1119449-40-9), with the molecular formula C19H18N2O3 and a molecular weight of 322.36 g/mol, is a heterocyclic building block used in chemical synthesis. Its structure incorporates a piperazine ring functionalised with an Fmoc protecting group and a ketone. This compound serves as a valuable intermediate in the development of more complex molecules, particularly within pharmaceutical research and organic synthesis endeavours.
- IUPAC
- 1-(9-Fluorenylmethoxycarbonyl)-3-oxopiperazine,4-Fmoc-2-oxopiperazine
- Synonyms
- 1-(9-Fluorenylmethoxycarbonyl)-3-oxopiperazine4-Fmoc-2-oxopiperazine

Organic Synthesis Intermediate
1-Fmoc-3-oxopiperazine is employed as a key building block in multi-step organic synthesis. Its distinct functional groups allow for selective derivatisation and incorporation into larger molecular architectures.
Pharmaceutical Research
This compound is utilised in the research and development of novel pharmaceutical agents. It can serve as a precursor for creating diverse heterocyclic scaffolds with potential biological activity.
Peptide Chemistry
The Fmoc protecting group suggests potential applications in solid-phase peptide synthesis or related areas where controlled introduction of modified amino acid surrogates is required.
| Molecular weight | 322.36 |
|---|---|
| Empirical formula | C19H18N2O3 |
| Assay | 97% |
| Melting point | 124 °C |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 36/37/38-50/53 |
| Safety statements (S) | 26-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Fmoc-3-oxopiperazine used for?
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1-Fmoc-3-oxopiperazine is primarily used as a building block in organic synthesis and in pharmaceutical research for developing new chemical entities.
What is the CAS number and molecular formula for 1-Fmoc-3-oxopiperazine?
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The CAS number for 1-Fmoc-3-oxopiperazine is 1119449-40-9, and its molecular formula is C19H18N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Fmoc-3-oxopiperazine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 1-Fmoc-3-oxopiperazine be handled?
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Handle 1-Fmoc-3-oxopiperazine with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation. It is classified with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), H335 (may cause respiratory irritation), and H400 (very toxic to aquatic life).
How is 1-Fmoc-3-oxopiperazine packed and shipped?
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1-Fmoc-3-oxopiperazine is typically packed for safe transport according to international regulations and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 1-Fmoc-3-oxopiperazine?
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Please contact our sales team via the website or direct inquiry to request a sample or obtain a quotation for 1-Fmoc-3-oxopiperazine.
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