1-Fluoropyridinium triflate
1-Fluoropyridinium triflate (CAS: 107263-95-6), with the empirical formula C6H5F4NO3S and a molecular weight of 247.17 g/mol, is a potent electrophilic fluorinating reagent. It is widely employed in synthetic organic chemistry for the efficient introduction of fluorine atoms into various organic molecules. Its utility makes it a valuable tool in the development of new pharmaceuticals and agrochemicals.
- IUPAC
- 1-Fluoropyridinium trifluoromethanesulfonate

Electrophilic Fluorination
Serves as a general-purpose electrophilic fluorinating agent in organic synthesis. It enables the controlled introduction of fluorine into organic substrates, which is crucial for modifying molecular properties.
Synthesis of Fluorinated Compounds
Used in the preparation of diverse fluorinated organic molecules. Fluorine incorporation can significantly alter lipophilicity, metabolic stability, and binding affinity of drug candidates.
Reagent for Chemical Synthesis
A versatile synthetic reagent widely utilised in academic and industrial research laboratories. Its reactivity profile supports a range of fluorination reactions.
| Molecular weight | 247.17 |
|---|---|
| Empirical formula | C6H5F4NO3S |
| Assay | 99% |
| Application | General purpose electrophilic fluorinating reagent.4 |
| Melting point | 185-186 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 35 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Fluoropyridinium triflate primarily used for?
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1-Fluoropyridinium triflate is primarily used as a general-purpose electrophilic fluorinating reagent in organic synthesis.
What is the CAS number and chemical formula for 1-Fluoropyridinium triflate?
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The CAS number is 107263-95-6 and the chemical formula is C6H5F4NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Fluoropyridinium triflate with an assay of 99%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 1-Fluoropyridinium triflate be handled safely?
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1-Fluoropyridinium triflate is classified as corrosive (H314) and requires stringent safety measures. Always use appropriate personal protective equipment, including eyeshields, face shields, and gloves. Ensure adequate ventilation and use a full-face particle respirator (N100 US or P3 EN143) when handling this substance. Refer to the Safety Data Sheet for detailed handling instructions.
Is 1-Fluoropyridinium triflate a controlled substance?
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The provided data does not indicate that 1-Fluoropyridinium triflate is a controlled substance.
How is 1-Fluoropyridinium triflate packed and shipped?
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1-Fluoropyridinium triflate is shipped according to international regulations for hazardous materials, classified as UN 3261, Class 8, Packing Group II. Specific packaging details can be provided upon request.
How can I request a quote or sample of 1-Fluoropyridinium triflate?
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Please contact our sales team via the website or email to request a quote or sample. Kindly provide your shipping details and intended use.
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