1-Fmoc-(S)-azetidine-2-carboxylic acid

CAS 136552-06-2C19H17NO4Chemical Synthesis

1-Fmoc-(S)-azetidine-2-carboxylic acid (CAS: 136552-06-2, Formula: C19H17NO4, MW: 323.34) is a protected unnatural amino acid derivative. It is widely utilised as a building block in peptide synthesis and in chemical biology research. This compound is essential for incorporating modified amino acid residues into peptide chains, enabling the study of protein structure-function relationships and the development of novel peptidomimetics.

IUPAC: 1-Fmoc-L-azetidine-2-carboxylic acid

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1-Fmoc-(S)-azetidine-2-carboxylic acid (C19H17NO4) — chemical structure, CAS 136552-06-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisOthersPeptide Chemistry

01 /Applications

Peptide Synthesis

Serves as a crucial building block for introducing azetidine-2-carboxylic acid into peptide sequences, facilitating the creation of novel peptides with modified structures and properties.

Chemical Biology

Utilised in research to probe biological systems and develop peptidomimetics, aiding in the study of protein interactions and drug discovery.

Organic Synthesis

A versatile intermediate for the synthesis of complex organic molecules and pharmaceutical compounds where azetidine moieties are required.

Drug Discovery

Incorporated into potential drug candidates to modify pharmacokinetic properties or enhance target binding affinity.

02 /Properties

Molecular weight	323.34
Empirical formula	C19H17NO4
Assay	≥97.0%

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

136552-06-2

MDL number

MFCD01320843

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-Fmoc-(S)-azetidine-2-carboxylic acid used for?

1-Fmoc-(S)-azetidine-2-carboxylic acid is primarily used as a building block in peptide synthesis and in chemical biology research for creating modified peptides and peptidomimetics.

What are the CAS number and formula for 1-Fmoc-(S)-azetidine-2-carboxylic acid?

The CAS number is 136552-06-2 and the empirical formula is C19H17NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1-Fmoc-(S)-azetidine-2-carboxylic acid with an assay of ≥97.0%. This product is supplied for research and laboratory use; it is not represented as USP, BP, EP, or pharmacopoeia grade.

How should 1-Fmoc-(S)-azetidine-2-carboxylic acid be handled safely?

Handle with appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound is classified as an irritant to skin, eyes, and the respiratory tract (H315, H319, H335).