SKF-89976A

CAS 85375-15-1C22H25NO2 · HClCell Biology

SKF-89976A (CAS: 85375-15-1), a white solid with the molecular formula C22H25NO2 · HCl and a molecular weight of 371.90, is a research chemical primarily used in neuroscience and cell biology. It acts as a selective antagonist for certain receptors, aiding in the study of neurotransmission and cellular signaling pathways. Its specific application includes investigating the role of adenosine receptors in GABA transport mechanisms.

IUPAC: 1-(4,4-Diphenyl-3-butenyl)-3-piperidinecarboxylic acid hydrochloride
Synonyms: 1-(4,4-Diphenyl-3-butenyl)-3-piperidinecarboxylic acid hydrochloride

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SKF-89976A (C22H25NO2 · HCl) — chemical structure, CAS 85375-15-1; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBioactive Small MoleculesCell BiologyGABAergicsGlaxoSmithKlineIon ChannelsLigand-Gated Ion ChannelsNeuroscienceNeurotransmissionNeurotransmitters

01 /Applications

Neuroscience Research

SKF-89976A is utilised to probe the complexities of neurotransmission and receptor function within the central nervous system. Its antagonist properties are valuable for understanding neuronal signalling pathways.

Cell Biology Studies

This compound serves as a tool in cell biology to investigate the intricate mechanisms of cell signaling. It aids in understanding the function of specific ion channels and receptor interactions.

GABA Transport Mechanism Investigation

SKF-89976A has been employed to study the influence of adenosine receptors on the transport of GABA, a key inhibitory neurotransmitter, contributing to research in neuropharmacology.

02 /Properties

Molecular weight	371.90
Empirical formula	C22H25NO2 · HCl
Assay	>98% (HPLC)
Form	solid
Colour	white
Solubility	DMSO: soluble20 mg/mLH2O: insoluble
Storage temperature	2-8°C
Application	SKF-89976A was used to study the role of adenosine receptors in uptake of GABA transport.4,5

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

85375-15-1

MDL number

MFCD01321071

05 /Additional specifications

Gene Information	human ... SLC6A1(6529), SLC6A11(6538), SLC6A12(6539)rat ... Slc6a1(79212), Slc6a12(50676)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is SKF-89976A used for?

SKF-89976A is used in research for its antagonist properties, particularly in neuroscience to study neurotransmission, cell signalling, and the role of adenosine receptors in GABA transport.

What is the CAS number and molecular formula for SKF-89976A?

The CAS number for SKF-89976A is 85375-15-1, and its molecular formula is C22H25NO2 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies SKF-89976A with a purity of >98% (HPLC). This is a research grade chemical and not represented as USP, BP, or EP.

How should SKF-89976A be handled and stored?

Handle SKF-89976A with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.

Is SKF-89976A a controlled substance?

The provided data does not indicate that SKF-89976A is a controlled substance.

How are chemicals like SKF-89976A packed, shipped, and exported?

Tech Serve Solutions securely packages chemicals for safe transport and complies with all regulations for global export, ensuring product integrity and regulatory adherence.