BMS-345541

CAS 547757-23-3C14H17N5 · HClCell Biology

BMS-345541 (CAS: 547757-23-3), a chemical compound with the formula C14H17N5 · HCl and a molecular weight of 291.78 g/mol, is supplied by TSS as a powder. This molecule is recognised for its role in biological research, particularly in cell signaling and kinase biology. Its primary applications revolve around its function as an IKK inhibitor, making it a valuable tool for researchers investigating inflammatory pathways and related cellular processes.

IUPAC: N-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine hydrochloride

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BMS-345541 (C14H17N5 · HCl) — chemical structure, CAS 547757-23-3; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBristol-Myers SquibbCell BiologyI Kappa B Kinase (IKK)Kinase/Phosphatase Biology

01 /Applications

IKK Inhibition Studies

BMS-345541 serves as a potent inhibitor of I kappa B Kinase (IKK), a key enzyme in the NF-κB signaling pathway. This makes it an essential reagent for researchers studying inflammation, immune responses, and related cellular mechanisms.

Cell Signaling Research

As a modulator of kinase activity, BMS-345541 is utilised in cell biology to investigate complex signaling cascades. It aids in understanding the roles of serine/threonine kinases in various cellular functions and disease states.

Drug Discovery and Development

This compound, developed by Bristol-Myers Squibb, is recognised as an approved therapeutic/drug candidate. It may be used in preclinical research for the development of novel therapeutics targeting inflammatory conditions.

02 /Properties

Molecular weight	291.78
Empirical formula	C14H17N5 · HCl
Assay	≥98% (HPLC)
Form	powder
Solubility	DMSO: soluble18 mg/mLH2O: insoluble
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

547757-23-3

MDL number

MFCD07784499

05 /Additional specifications

Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is BMS-345541 used for?

BMS-345541 is primarily used as an I kappa B Kinase (IKK) inhibitor in research settings, particularly for studies in cell signaling, kinase biology, and inflammatory pathways.

What are the CAS number and formula for BMS-345541?

The CAS number for BMS-345541 is 547757-23-3, and its empirical formula is C14H17N5 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies BMS-345541 with an assay of ≥98% (HPLC). We do not represent this product as meeting any pharmacopoeia standards (e.g., USP, BP, EP).

What are the safety and handling recommendations for BMS-345541?

Handling BMS-345541 requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3, indicating a high hazard to water.

How is BMS-345541 shipped and exported?

BMS-345541 is typically stored at 2-8°C in a desiccated condition. TSS complies with all regulations for the safe packing, shipping, and export of this chemical.