Bis[2-(2-chloroethoxy)ethyl] ether
Bis[2-(2-chloroethoxy)ethyl] ether (CAS: 638-56-2) is an organic compound with the molecular formula O(CH2CH2OCH2CH2Cl)2 and a molecular weight of 231.12 g/mol. This dichloro ether serves as a versatile building block in organic synthesis. It is primarily utilised in the preparation of various complex organic molecules, including specific poly(ethoxy)ethanols and pyridinium compounds, making it a valuable reagent for research and development in chemical synthesis.
- IUPAC
- 1,11-Dichloro-3,6,9-trioxaundecane,Tetraethylene glycol dichloride
- Synonyms
- Tetraethylene glycol dichloride
![Bis[2-(2-chloroethoxy)ethyl] ether (O(CH2CH2OCH2CH2Cl)2) — chemical structure, CAS 638-56-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F638-56-2.png&w=3840&q=75)
Synthesis of Poly(ethoxy)ethanols
Bis[2-(2-chloroethoxy)ethyl] ether has been employed in the preparation of series of para-(1,1,3,3-tetramethylbutyl)-phenoxypoly(ethoxy)ethanols, serving as a key intermediate in the synthesis of these functionalised molecules.
Preparation of Pyridinium Compounds
This ether has been utilised in the synthesis of 1-(4-pyridiniumaldoxime)-2-(((2-chloroethoxy)-2-ethoxy)ethoxy)ethane, demonstrating its utility in the creation of complex heterocyclic structures.
Organic Synthesis Building Block
As a difunctionalised ether, Bis[2-(2-chloroethoxy)ethyl] ether is a useful building block for organic chemists, enabling the introduction of specific ether chains and terminal chloride functionalities into target molecules.
| Molecular weight | 231.12 |
|---|---|
| Linear formula | O(CH2CH2OCH2CH2Cl)2 |
| Assay | ≥99.0% (T) |
| Density | 1.18 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.464 |
| Application | Bis[2-(2-chloroethoxy)ethyl] ether was used in preparation of series of para-(1,1,3,3-tetramethylbutyl)-phenoxypoly(ethoxy)ethanols1. It was used in the synthesis of 1-(4-pyridiniumaldoxime)-2-(((2-chloroethoxy)-2-ethoxy)ethoxy)ethane2. |

Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 21-25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis[2-(2-chloroethoxy)ethyl] ether used for?
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Bis[2-(2-chloroethoxy)ethyl] ether is used as a building block in organic synthesis, particularly in the preparation of poly(ethoxy)ethanols and pyridinium compounds.
What are the CAS number and formula for Bis[2-(2-chloroethoxy)ethyl] ether?
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The CAS number is 638-56-2 and the linear formula is O(CH2CH2OCH2CH2Cl)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis[2-(2-chloroethoxy)ethyl] ether with an assay of ≥99.0% (T). This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should Bis[2-(2-chloroethoxy)ethyl] ether be handled?
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Bis[2-(2-chloroethoxy)ethyl] ether is classified as dangerous. It is toxic if swallowed (H301) and toxic in contact with skin (H312). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area and avoid exposure.
How is this chemical packed, shipped, and exported?
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Bis[2-(2-chloroethoxy)ethyl] ether is shipped as UN 2810, Class 6.1, Packing Group III. Tech Serve Solutions exports fine chemicals globally, adhering to all relevant transportation and export regulations.
How can I request a quote or sample?
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To request a quote or a sample of Bis[2-(2-chloroethoxy)ethyl] ether, please contact our sales department through the website or by phone, providing the product name and CAS number.
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