Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone
Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone (CAS 57683-72-4) is a homobifunctional cross-linking reagent with a molecular weight of 436.35 g/mol. It features two N-hydroxysuccinimide (NHS) ester groups, making it highly reactive towards primary amines. This compound is primarily utilized in chemical biology and protein modification for applications such as crosslinking proteins and stabilising molecular structures in research settings.
- IUPAC
- BSOCOES
![Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone (C14H16N2O12S) — chemical structure, CAS 57683-72-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F57683-72-4.png&w=3840&q=75)
Protein Crosslinking
Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone reacts with primary amines on protein surfaces, forming stable amide bonds. This allows for the covalent linkage of proteins, which is valuable for studying protein-protein interactions or stabilising protein complexes.
Surface Modification
The compound can be used to modify surfaces functionalised with amine groups. This enables the immobilisation of biomolecules or the creation of specific surface chemistries for assays and diagnostics.
Bioconjugation
Its ability to link amine-containing molecules makes it suitable for creating bioconjugates, such as linking peptides or small molecules to proteins for various research applications in molecular biology.
| Molecular weight | 436.35 |
|---|---|
| Empirical formula | C14H16N2O12S |
| Assay | ≥97.0% (CHN) |
| Storage temperature | −20°C |
| Melting point | 169-173 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone used for?
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Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone is used as a homobifunctional cross-linking reagent in chemical biology and protein modification for linking molecules containing primary amine groups.
What is the CAS number and formula for Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone?
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The CAS number is 57683-72-4 and the empirical formula is C14H16N2O12S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone with an assay of ≥97.0% (CHN). This is a research-grade chemical and not intended for pharmaceutical, food, or therapeutic use. TSS does not represent it as USP, BP, or EP grade.
How should Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone be handled and stored?
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This compound requires careful handling. Recommended personal protective equipment includes eyeshields and gloves. A respirator filter, such as type N95 (US) or type P1 (EN143), is advised. Store at -20°C to maintain stability.
Is Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone a controlled substance?
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The provided data does not indicate that Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone is a controlled substance.
How are your chemicals packed and shipped internationally?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, adhering to all necessary regulations for safe and compliant international shipping.
How can I request a sample or quote for this product?
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Please contact our sales team directly through the website to request a sample or a detailed quote for Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone.
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