L-Valine-15N
L-Valine-15N (CAS: 59935-29-4) is an isotopically labelled derivative of the essential amino acid L-valine. It features a 15N substitution, providing a distinct mass shift for use in analytical and biochemical research. This compound is invaluable for applications requiring precise tracking and quantification in mass spectrometry and NMR spectroscopy, particularly within proteomics and metabolic pathway studies.
Mass Spectrometry Studies
L-Valine-15N is employed as an internal standard or tracer in quantitative mass spectrometry. The 15N enrichment allows for accurate differentiation from unlabeled valine, enabling precise measurements in complex biological samples.
Biomolecular NMR Spectroscopy
The 15N label facilitates NMR studies of protein structure and dynamics. It allows researchers to follow the fate and incorporation of valine residues in protein synthesis and metabolism.
Proteomics and Metabolic Research
Used in stable isotope labeling techniques, such as SILAC, to quantify protein abundance changes. This helps in understanding cellular responses and metabolic pathways.
Drug Discovery and Development
Can be utilised in research settings to study drug metabolism and pharmacokinetic profiles by tracing the involvement of specific amino acid pathways.
| Molecular weight | 118.14 |
|---|---|
| Linear formula | (CH3)2CHCH(15NH2)CO2H |
| Optical activity | [α]25/D +26.6°, c = 1 in 5 M HCl |
| Melting point | 295-300 °C (subl.)(lit.) |
| Isotopic Purity | 98 atom % 15N |
|---|---|
| Mol Wt | mol wt 118.14 by atom % calculation |
| Mass Shift | M+1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Valine-15N used for?
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L-Valine-15N is primarily used in scientific research as a labelled compound for mass spectrometry and NMR spectroscopy, particularly in fields like proteomics, metabolic studies, and biomolecular analysis.
What are the CAS number and formula for L-Valine-15N?
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The CAS number for L-Valine-15N is 59935-29-4. The linear formula is (CH₃)₂CHCH(¹⁵NH₂)CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Valine-15N with a purity of 98 atom % 15N. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should L-Valine-15N be handled?
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L-Valine-15N has a WGK Germany classification of 1, indicating it is slightly hazardous to water. Standard laboratory precautions should be observed during handling to avoid exposure.
Is L-Valine-15N controlled or scheduled?
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The provided data does not indicate that L-Valine-15N is a controlled or scheduled substance.
How is L-Valine-15N packed and shipped?
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L-Valine-15N is typically supplied in appropriate laboratory packaging for safe transport and storage. TSS can export this chemical globally.
How can I request a sample or quote for L-Valine-15N?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for L-Valine-15N.
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