Bis[2-(4-azidosalicylamido)ethyl] disulfide
Bis[2-(4-azidosalicylamido)ethyl] disulfide (CAS: 199804-21-2), with the molecular formula C18H18N8O4S2 and a molecular weight of 474.52 g/mol, is a homobifunctional cross-linking reagent. It is employed in chemical biology and molecular biology for protein modification and structural analysis. This compound enables the covalent linkage of proteins, with potential for cleavable cross-links, facilitating advanced proteomic studies.
- IUPAC
- BASED,N, N′-(Dithiobis-ethylene)bis(4-azido-2-hydroxy-benzamide),N,N′-Bis(4-azidosalicoyl)cystamine
- Synonyms
- N,N′-(Dithiobis-ethylene)bis(4-azido-2-hydroxy-benzamide), N,N′-Bis(4-azidosalicoyl)cystamine
![Bis[2-(4-azidosalicylamido)ethyl] disulfide (C18H18N8O4S2) — chemical structure, CAS 199804-21-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F199804-21-2.png&w=3840&q=75)
Protein Cross-linking
This reagent is utilised for the cross-linking of proteins, allowing for the study of protein-protein interactions and the stabilisation of protein structures. The disulfide bond offers a unique cleavage point within the cross-link.
Molecular Biology Research
It serves as a valuable tool in molecular biology for protein modification and structural analysis. Its application aids in understanding complex biological systems and pathways.
Proteomics and Structural Studies
The compound is instrumental in proteomics, enabling researchers to investigate protein complexes and map structural relationships within biological samples. It aids in protein structural analysis by providing stable linkages.
| Molecular weight | 474.52 |
|---|---|
| Empirical formula | C18H18N8O4S2 |
| Assay | ≥95.0% (HPLC) |
| Storage temperature | 2-8°C |
| Application | Reagent for cross linking of proteins; the cross link can be cleaved1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis[2-(4-azidosalicylamido)ethyl] disulfide used for?
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Bis[2-(4-azidosalicylamido)ethyl] disulfide is used as a reagent for cross-linking proteins in chemical biology and molecular biology research. It is employed in protein modification, structural analysis, and proteomics.
What is the CAS number and molecular formula for Bis[2-(4-azidosalicylamido)ethyl] disulfide?
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The CAS number for Bis[2-(4-azidosalicylamido)ethyl] disulfide is 199804-21-2, and its molecular formula is C18H18N8O4S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis[2-(4-azidosalicylamido)ethyl] disulfide with a purity of ≥95.0% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety precautions when handling Bis[2-(4-azidosalicylamido)ethyl] disulfide?
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When handling this compound, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used, and the substance is classified under WGK Germany 3, indicating a high hazard to water.
How is Bis[2-(4-azidosalicylamido)ethyl] disulfide shipped and exported?
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Bis[2-(4-azidosalicylamido)ethyl] disulfide is stored at 2-8°C. As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and documentation for international shipment.
How can I request a sample or a quote for Bis[2-(4-azidosalicylamido)ethyl] disulfide?
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To request a sample or a quote for Bis[2-(4-azidosalicylamido)ethyl] disulfide, please contact our sales department through the website or by phone.
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