(S)-(−)-Methylsuccinic acid
(S)-(−)-Methylsuccinic acid (CAS 2174-58-5), a chiral dicarboxylic acid with the formula HO2CCH2CH(CH3)CO2H and a molecular weight of 132.11 g/mol, is a valuable building block in organic synthesis. Its defined stereochemistry makes it particularly useful in asymmetric synthesis, enabling the creation of enantiomerically pure compounds. This compound serves as a key intermediate in the development of complex molecules across various chemical research and development sectors.

Chiral Building Block
(S)-(−)-Methylsuccinic acid is extensively employed as a chiral synthon in the construction of stereochemically defined organic molecules. Its inherent chirality is critical for synthesising enantiopure pharmaceuticals and agrochemicals.
Asymmetric Synthesis
This compound is a vital reagent in asymmetric synthesis, facilitating the introduction of chirality into target molecules. It enables chemists to control the stereochemical outcome of reactions with high fidelity.
Organic Synthesis Intermediate
It functions as a versatile intermediate in multi-step organic syntheses. Its dicarboxylic acid functionality allows for diverse chemical transformations, leading to a wide array of complex organic structures.
| Molecular weight | 132.11 |
|---|---|
| Linear formula | HO2CCH2CH(CH3)CO2H |
| Assay | 99% |
| Optical activity | [α]20/D −8.3°, c = 5.1 in H2O |
| Melting point | 110-115 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-Methylsuccinic acid used for?
+
(S)-(−)-Methylsuccinic acid is primarily used as a chiral building block and an intermediate in asymmetric organic synthesis, particularly for creating enantiomerically pure compounds for research and development.
What are the CAS number and formula for (S)-(−)-Methylsuccinic acid?
+
The CAS number for (S)-(−)-Methylsuccinic acid is 2174-58-5, and its linear formula is HO2CCH2CH(CH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-(−)-Methylsuccinic acid with a purity of 99%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeia standards.
What are the safety and handling requirements for (S)-(−)-Methylsuccinic acid?
+
This compound is classified as a Warning, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves. Ensure adequate ventilation.
How is (S)-(−)-Methylsuccinic acid packaged and shipped?
+
Tech Serve Solutions carefully packages and exports (S)-(−)-Methylsuccinic acid in compliance with international shipping regulations for chemicals.
How can I request a quote or sample?
+
To request a quote or sample of (S)-(−)-Methylsuccinic acid, please contact our sales department through the website or via email, providing your contact details and the quantity required.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis