(S)-(−)-Methioninol
(S)-(−)-Methioninol (CAS: 2899-37-8), a chiral amino alcohol with the linear formula CH3SCH2CH2CH(NH2)CH2OH and a molecular weight of 135.23 g/mol, is a valuable building block in organic synthesis. It serves as a key intermediate in the preparation of various complex molecules, particularly in the fields of peptide chemistry and chemical biology. Its defined stereochemistry makes it indispensable for stereoselective synthesis.
- IUPAC
- (S)-(−)-2-Amino-4-methylthio-1-butanol,(S)-2-Amino-4-methylmercapto-1-butanol,L-Methioninol
- Synonyms
- (S)-(−)-2-Amino-4-methylthio-1-butanol(S)-2-Amino-4-methylmercapto-1-butanolL-Methioninol

Peptide Synthesis
As a derivative of methionine, (S)-(−)-Methioninol is utilised in the synthesis of peptides, particularly those requiring specific structural modifications or containing non-proteinogenic amino acids. Its chiral nature ensures stereochemical integrity during peptide coupling.
Chiral Building Block
This compound serves as a versatile chiral synthon in the construction of enantiomerically pure molecules. Its amino and alcohol functionalities, along with the thioether side chain, allow for diverse chemical transformations.
Chemical Biology Research
It is employed in research settings for developing probes and modified biomolecules. The unique structural features can be leveraged to study biological processes or to create novel bioactive compounds.
Organic Synthesis Intermediate
The molecule acts as a precursor in multi-step syntheses of pharmaceuticals and other fine chemicals. Its availability supports the development of new chemical entities and process optimisation.
| Molecular weight | 135.23 |
|---|---|
| Linear formula | CH3SCH2CH2CH(NH2)CH2OH |
| Assay | 98% |
| Refractive index | n20/D 1.5216(lit.) |
| Optical activity | [α]21/D −12.7°, c = 1.4 in ethanol |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-Methioninol used for?
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(S)-(−)-Methioninol is primarily used as a chiral building block and intermediate in organic synthesis, particularly in peptide chemistry and chemical biology research for creating complex, enantiomerically pure molecules.
What is the CAS number and formula for (S)-(−)-Methioninol?
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The CAS number for (S)-(−)-Methioninol is 2899-37-8, and its linear formula is CH3SCH2CH2CH(NH2)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-Methioninol with an assay of 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(−)-Methioninol be handled safely?
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Safe handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The flash point is 113 °C (235.4 °F).
How is (S)-(−)-Methioninol packed and shipped?
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Tech Serve Solutions exports and ships fine chemicals globally, adhering to all necessary regulations for safe transport. Specific packaging details are available upon request.
How can I request a sample or quote for (S)-(−)-Methioninol?
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To request a sample or obtain a quote for (S)-(−)-Methioninol, please contact the TSS sales team through our website or by phone.
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