(S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine
(S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine (CAS 81510-19-2) is a chiral phosphine ligand with a molecular weight of 545.63. It is a key reagent in asymmetric synthesis and catalysis, particularly valued for its efficacy in stereoselective reductions and other chiral transformations. Supplied by Tech Serve Solutions with an assay of ≥98.0% (CHN), this compound is essential for researchers and industrial chemists engaged in developing enantiomerically pure substances.
- IUPAC
- (S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-α-methylbenzylamine
- Synonyms
- (S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-α-methylbenzylamine

Asymmetric Catalysis
This chiral phosphine ligand is extensively employed as a component in transition metal catalysts for asymmetric reactions, enabling the synthesis of enantiomerically enriched products.
Stereoselective Synthesis
It plays a crucial role in stereoselective transformations, facilitating the formation of specific enantiomers or diastereomers in organic synthesis pathways.
Ligand for Metal Complexes
As a bidentate phosphine ligand, it forms stable complexes with various transition metals, which are then utilised as catalysts in a wide array of organic reactions.
Chiral Reagent
Its unique chiral structure makes it an effective reagent for inducing chirality in synthetic processes, particularly in the development of pharmaceuticals and fine chemicals.
| Molecular weight | 545.63 |
|---|---|
| Empirical formula | C36H37NP2 |
| Assay | ≥98.0% (CHN) |
| Optical activity | [α]20/D −4.5±0.7°, c = 1% in acetone |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine used for?
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(S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine is primarily used in asymmetric synthesis and catalysis, acting as a chiral ligand for metal complexes in stereoselective reactions and transformations.
What is the CAS number and formula for this compound?
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The CAS number is 81510-19-2 and the empirical formula (Hill notation) is C36H37NP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥98.0% (CHN). This is a technical/research grade; TSS does not represent it as USP/BP/EP.
How should (S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine be handled?
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This compound is classified as Danger, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 or P3 filters), is mandatory during handling.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product.
How can I request a sample or quote for this product?
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Please contact our sales department directly via phone or email to request a sample or obtain a quotation for (S)-(−)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine.
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