2-(Boc-aminomethyl)phenylacetic acid
2-(Boc-aminomethyl)phenylacetic acid (CAS: 40851-66-9), with the molecular formula C14H19NO4 and a molecular weight of 265.30 g/mol, is a valuable derivative in organic synthesis. This compound is primarily utilised as a building block in peptide chemistry and for the creation of unnatural amino acid derivatives. Its protected amine functionality makes it a versatile reagent in complex synthetic routes within chemical biology and broader chemical synthesis.

Peptide Synthesis
Serves as a key intermediate in the synthesis of peptides, particularly those incorporating unnatural amino acid residues. Its Boc-protected amine allows for selective deprotection and subsequent coupling reactions.
Chemical Biology Research
Utilised in the construction of more complex molecules for biochemical studies. Its structure can be incorporated into probes or modified substrates to investigate biological pathways.
Organic Synthesis Building Block
Acts as a versatile synthon for introducing specific structural motifs in the development of novel organic compounds. Suitable for a range of synthetic transformations.
Unnatural Amino Acid Derivatives
A direct precursor for generating a variety of unnatural amino acids, which are crucial for developing novel pharmaceuticals and materials with tailored properties.
| Molecular weight | 265.30 |
|---|---|
| Empirical formula | C14H19NO4 |
| Assay | ≥99.0% (HPLC)≥99.0%99.0-101.0% (NaOH 0.1 M, T) |
| Impurities tested | ≤0.5% water |

Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Boc-aminomethyl)phenylacetic acid used for?
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2-(Boc-aminomethyl)phenylacetic acid is primarily used as a building block in peptide chemistry, for synthesising unnatural amino acid derivatives, and in broader chemical synthesis and chemical biology research.
What is the CAS number and molecular formula for this compound?
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The CAS number is 40851-66-9 and the molecular formula is C14H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Boc-aminomethyl)phenylacetic acid with an assay of ≥99.0% (HPLC) and typically ≤0.5% water content. This product is supplied for research and development purposes and is not intended for pharmaceutical, food, or any other regulated use unless explicitly stated otherwise.
What are the primary safety concerns when handling 2-(Boc-aminomethyl)phenylacetic acid?
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According to GHS, this compound is classified as Warning, with hazards including H302 (Harmful if swallowed) and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
How is 2-(Boc-aminomethyl)phenylacetic acid typically packed and shipped?
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Tech Serve Solutions packages and exports this chemical in compliance with international shipping regulations. Packaging is designed to maintain product integrity and safety during transit.
How can I request a sample or a quote for 2-(Boc-aminomethyl)phenylacetic acid?
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To request a sample or obtain a quotation, please contact our sales department through the website or by direct enquiry, providing your specific requirements and contact details.
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