2-(Boc-amino)ethanethiol
2-(Boc-amino)ethanethiol (CAS 67385-09-5), with the linear formula HSCH2CH2NHCO2C(CH3)3, is a key organic building block with a molecular weight of 177.26 g/mol. This thiol-carbamate derivative is valuable in chemical synthesis and chemical biology for introducing a protected thiol group. Its bifunctional nature makes it an essential linker in various coupling reactions for creating complex molecules and advanced materials.
- IUPAC
- tert-Butyl N-(2-mercaptoethyl)carbamate
- Synonyms
- tert-Butyl N-(2-mercaptoethyl)carbamate
Peptide Synthesis
Serves as a building block for incorporating cysteine residues or thiol-reactive functionalities into peptides, crucial for studies in chemical biology and drug development.
Bioconjugation
Facilitates the conjugation of biomolecules through its thiol group, enabling the creation of antibody-drug conjugates, protein labels, and diagnostic probes.
Surface Modification
Used to functionalize surfaces with thiol groups, allowing for subsequent attachment of biomolecules or nanoparticles, important in sensor development and biomaterials.
Organic Synthesis Intermediate
A versatile intermediate for the synthesis of various sulfur-containing organic compounds and heterocyclic structures in research and development settings.
| Molecular weight | 177.26 |
|---|---|
| Linear formula | HSCH2CH2NHCO2C(CH3)3 |
| Assay | 97% |
| Boiling point | 68 °C/0.3 mmHg(lit.) |
| Density | 1.049 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.474(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Boc-amino)ethanethiol used for?
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2-(Boc-amino)ethanethiol is primarily used as a bifunctional linker and building block in organic synthesis, peptide synthesis, bioconjugation, and surface modification due to its protected thiol group.
What is the CAS number and formula for 2-(Boc-amino)ethanethiol?
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The CAS number is 67385-09-5 and the linear formula is HSCH2CH2NHCO2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Boc-amino)ethanethiol with an assay of 97%. This is a research-grade material and is not represented as USP, BP, or EP grade.
How should 2-(Boc-amino)ethanethiol be handled safely?
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2-(Boc-amino)ethanethiol is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use with adequate ventilation, wear appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Refer to the safety data sheet for comprehensive handling instructions.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions expertly packs and exports chemicals globally, adhering to all relevant shipping regulations to ensure safe and timely delivery to your research or manufacturing facility.
How can I request a sample or quote for 2-(Boc-amino)ethanethiol?
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To request a sample or a quote, please visit the product page on our website and use the designated inquiry form, or contact our sales team directly.
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