(R)-(+)-5,5′-Dichloro-2,2′-bis(diphenylphosphino)-6,6′-dimethoxy-1,1′-biphenyl
(R)-(+)-5,5′-Dichloro-2,2′-bis(diphenylphosphino)-6,6′-dimethoxy-1,1′-biphenyl (CAS: 185913-97-7), a chiral phosphine ligand with the molecular formula C38H30Cl2O2P2, is instrumental in asymmetric synthesis. Its unique structure facilitates high enantioselectivity in various catalytic transformations. This compound is a valuable reagent for chemists developing sophisticated synthetic routes, particularly in the pharmaceutical and fine chemical industries, enabling the production of stereochemically pure compounds.
- IUPAC
- (+)-(5,5′-Dichloro-6,6′-dimethoxy-1,1′-biphenyl)-2,2′-diyl-bis(diphenylphosphine),(+)-2,2′-Bis(diphenylphosphino)-5,5′-dichloro-6,6′-dimethoxy-1,1′-biphenyl,(R)-(+)-Cl-MeO-BIPHEP
- Synonyms
- (+)-2,2′-Bis(diphenylphosphino)-5,5′-dichloro-6,6′-dimethoxy-1,1′-biphenyl(+)-(5,5′-Dichloro-6,6′-dimethoxy-1,1′-biphenyl)-2,2′-diyl-bis(diphenylphosphine)(R)-(+)-Cl-MeO-BIPHEP
Asymmetric Catalysis
This chiral diphosphine ligand is employed in transition metal-catalyzed asymmetric reactions, such as hydrogenation, hydroformylation, and C-C bond formation. It promotes the synthesis of enantiomerically enriched products crucial for pharmaceuticals.
Chiral Synthesis
As a key component in asymmetric synthesis, it enables the controlled creation of chiral centres. This is vital for producing single enantiomers of biologically active molecules where stereochemistry dictates efficacy.
Ligand for Metal Complexes
It serves as a versatile ligand, coordinating with various transition metals to form active catalytic species. The specific electronic and steric properties of this biphenyl derivative influence catalyst performance and selectivity.
| Molecular weight | 651.50 |
|---|---|
| Empirical formula | C38H30Cl2O2P2 |
| Assay | ≥95.0% (H-NMR) |
| Optical activity | [α]/D +59±4°, c = 1% in chloroform |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-5,5′-Dichloro-2,2′-bis(diphenylphosphino)-6,6′-dimethoxy-1,1′-biphenyl primarily used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis to promote enantioselective synthesis of valuable chemical compounds.
What are the CAS number and chemical formula for this product?
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The CAS number is 185913-97-7, and the empirical formula is C38H30Cl2O2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥95.0% (H-NMR). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-(+)-5,5′-Dichloro-2,2′-bis(diphenylphosphino)-6,6′-dimethoxy-1,1′-biphenyl be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection. The substance is classified with WGK 3 (Germany).
Is this chemical available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product.
How can I request a sample or a quote for this chemical?
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Please contact our sales team through the website or by phone to request a sample or obtain a quotation.
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