(R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone
(R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone (CAS 223906-37-4) is a chiral auxiliary with a molecular weight of 253.30 g/mol. This compound is primarily utilised in asymmetric synthesis for the stereoselective construction of complex organic molecules. Its specific structure allows for high levels of enantiocontrol in various chemical transformations, making it a valuable reagent in organic chemistry research and development.
- Synonyms
- C16H15NO2
Chiral Auxiliary in Asymmetric Synthesis
This oxazolidinone derivative serves as an effective chiral auxiliary, enabling the stereoselective synthesis of optically active compounds. It is employed to control the stereochemical outcome of reactions such as alkylations, aldol additions, and Michael additions.
Stereoselective Alkylations
It facilitates highly enantioselective alkylation reactions when attached to a substrate, guiding the incoming electrophile to a specific face of the molecule.
Synthesis of Chiral Building Blocks
The compound is instrumental in the preparation of enantiomerically pure building blocks, which are essential for the synthesis of pharmaceuticals and other fine chemicals.
| Molecular weight | 253.30 |
|---|---|
| Empirical formula | C16H15NO2 |
| Assay | 97% |
| Optical activity | [α]20/D +300°, c = 1 in chloroform |
| Melting point | 268-272 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone used for?
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This compound is primarily used as a chiral auxiliary in asymmetric synthesis to control stereochemistry in the formation of new chiral centres.
What is the CAS number and molecular formula?
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The CAS number is 223906-37-4, and the empirical formula is C16H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions?
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Recommended personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is advised. The compound is classified under WGK Germany 3.
How is this product packed, shipped, and exported?
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We ensure secure and compliant packaging for domestic and international shipments, adhering to all relevant regulations for chemical export.
How can I request a quote or sample?
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Please use the 'Request a Quote' or 'Request a Sample' buttons on our website, or contact our sales team directly.
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